Evidence map›Paper›PMID 28466136›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017

Comparison of total, free and bioavailable 25-OH vitamin D determinations to evaluate its biological activity in healthy adults: the LabOscat study.

P Peris, X Filella, A Monegal, N Guañabens, L Foj, M Bonet, D Boquet, E Casado, D Cerdá, A Erra and 9 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Observational
  4. Haplotypes in theNutrients · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

P PerisHospital Clínic de Barcelona, IDIBAPS. CIBERehd, Barcelona, Spain. pperis@clinic.ub.es.
X FilellaServicio de Bioquímica Clínica, Hospital Clinic, Barcelona, Spain.
A MonegalHospital Clínic de Barcelona, IDIBAPS. CIBERehd, Barcelona, Spain.
N GuañabensHospital Clínic de Barcelona, IDIBAPS. CIBERehd, Barcelona, Spain.
L FojServicio de Bioquímica Clínica, Hospital Clinic, Barcelona, Spain.
M BonetHospital de l'Alt Penedés, Barcelona, Spain.
D BoquetHospital Arnau de Vilanova, Lleida, Spain.
E CasadoInstituto Universitario Parc Taulí, Barcelona, Spain.
D CerdáHospital Moisés Broggi, Barcelona, Spain.
A ErraHospital Universitari de Bellvitge, Barcelona, Spain. aerra@hsrafael.es.
C Gómez-VaqueroHospital San Rafael, Madrid, Spain.
S MartínezHospital Mútua de Terrassa, Madrid, Spain.
N MontaláHospital Sta María, Barcelona, Spain.
C PittarchHospital Esperit Sant, Barcelona, Spain.
E KanterewiczHospital de Vic, Barcelona, Spain.
M SalaHospital de Figueres, Barcelona, Spain.
X SurisHospital de Ganollers, Catalonia, Spain.
J L CarrascoDepartament de Fonaments Clínics, Universitat de Barcelona, Barcelona, Spain.
LabOscat Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determination of different forms of 25-OHD (total, free and bioavailable) in healthy young women does not offer additional advantages over standard 25-OHD

introductionDetermination of 25-OH vitamin D serum levels (25-OHD) constitutes the method of choice for evaluating vitamin D deficiency. However, vitamin D-binding protein (DBP) may modulate its bioavailability thereby affecting correct evaluation of 25-OHD status. We analysed the impact of the determination of 25-OHD (total, free and bioavailable) on the evaluation its biologic activity (estimated by serum PTH determination) in healthy young women.

methods173 premenopausal women (aged 35-45 yrs.) were included. We analysed serum values of total 25-OHD (25-OHD

results62% of subjects had 25-OHD values <20 ng/ml and also had significantly lower 25-OHD

conclusionsDetermination of different forms of 25-OHD in healthy young women does not offer additional advantages over standard 25-OHD

Indexed as

AdultBiological AvailabilityBiomarkersFemaleHumansMiddle AgedParathyroid HormonePremenopauseVitamin DVitamin D Deficiency25-hydroxyvitamin DBiomarkersParathyroid HormoneVitamin D25-Hydroxyvitamin DBioavailable vitamin DDBPFree vitamin DVitamin D deficiencyVitamin D insufficiency

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.