ReviewJournal of cardiovascular echography
How to Understand Patent Foramen Ovale Clinical Significance: Part I.
Review in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Article
- Patent Foramen Ovale and Other Cardiopathies as Causes of Embolic Stroke With Unknown Source.Journal of stroke · 2024Review
- Reviewing migraine-associated pathophysiology and its impact on elevated stroke risk.Frontiers in neurology · 2024Review
- Heart Brain Clinic: An Integrated Approach to Stroke Care.Neurology. Clinical practice · 2023Article
- Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management.Journal of clinical medicine · 2023Review
- Article
- Patent foramen ovale: anatomical complexity and long-tunnel morphology related issues.American journal of cardiovascular disease · 2021Review
- The Presence of Patent Foramen Ovale in the Superior Type of Sinus Venosus Atrial Septal Defect.The journal of Tehran Heart Center · 2020Article
- A Case of Complex PFO Leading to Ischemic Stroke: A Practical Clinical Pearl for Neurohospitalists.The Neurohospitalist · 2016Article
- How to do echo for patent foramen ovale: Pre, Intra and Postprocedure: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging.Journal of cardiovascular echographyArticle
- Transcranial Doppler Ultrasound: Incremental Diagnostic Role in Cryptogenic Stroke Part II.Journal of cardiovascular echographyReview
- How to Understand Patent Foramen Ovale Clinical Significance - Part II: Therapeutic Strategies in Cryptogenic Stroke.Journal of cardiovascular echographyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patent foramen ovale (PFO) is a remnant of fetal circulation commonly found in healthy population. However, a large number of clinical conditions have been linked to PFO, the most important being ischemic strokes of undetermined cause (cryptogenic strokes) and migraine, especially migraine with aura. Coexistent atrial septal aneurysm, size of PFO, degree of the shunt, shunt at rest, pelvic deep vein thrombosis, and prothrombotic states (G20210A prothrombin gene mutation, Factor V Leiden mutation, MTHFR: C677T, basal homocystine, recent surgery, trauma, or use of contraceptives) could enhance stroke risk in subjects with PFO. Owing to the complexity of this issue, for any individual presenting with a PFO, particularly in the setting of cryptogenic stroke, it is not clear whether the PFO is pathogenically related to the neurological event or an incidental finding. Thus, a heart-brain team, which individually plans the best strategy, in accordance with neuroimaging findings and anatomical characteristics of PFO, is strongly recommended. In the first part of this review, we discuss the embryologic and anatomic features of PFO, the diagnostic techniques for its identification and evaluation, and the relationship between PFO and neurological syndromes. A special attention is made to provide some key points, useful in a daily clinical practice, which summarize how better we understand PFO clinical significance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.