Evidence map›Paper›PMID 28465792›Full record

ArticleWorld journal of diabetes2017

Effects of intermittent fasting on health markers in those with type 2 diabetes: A pilot study.

Terra G Arnason, Matthew W Bowen, Kerry D Mansell

7 registry-linked trialsOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 65 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 6 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03938441 naterminatednot on this mapstarted 2019, after this paper: background citation

Biweekly Interval Intermittent Fasting for Type 2 Diabetes, a Safety Study

TypeinterventionalSponsorgino gaddiniRan2019 to 2021Enrolled24ConditionsDiabetes Type 2, Pre-diabetesArmsIntermittent Fasting
NCT03940482 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Time Restricted Eating As Treatment (TREAT) for Diabetes Mellitus: A Pre-Post 12 Week Study on the Effectiveness of Intermittent Fasting in Asians With Type 2 Diabetes Mellitus

TypeinterventionalSponsorSingapore General HospitalRan2019 to 2023Enrolled50ConditionsType 2 Diabetes MellitusArmsTime Restricted Eating As Treatment (TREAT) for Diabetes.
NCT04011995 nacompletednot on this mapstarted 2018, after this paper: background citation

Effects of Intermittent Caloric Restriction in Youth With Cardiometabolic Risk: a Randomized Controlled Pilot Study

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2018 to 2021Enrolled34ConditionsOverweight, Obesity, Cardiometabolic RiskArmsIntermittent caloric restriction, Low carbohydrate diet, Health education on reducing the cardiometabolic risk
NCT04247464 nacompletednot on this mapstarted 2020, after this paper: background citation

Evaluation of Short-term Fasting Effects on Chemotherapy Toxicity and Efficacy

TypeinterventionalSponsorIMDEA FoodRan2020 to 2023Enrolled11ConditionsFastingArmsFasting
NCT04259879 nacompletednot on this map

Evaluation of p21 Induction and Molecular Pathways Related to Short-term Fasting Response

TypeinterventionalSponsorIMDEA FoodRan2016 to 2016Enrolled20ConditionsFastingArmsFasting
NCT05124847 nacompletednot on this mapstarted 2021, after this paper: background citation

Time Restricted Eating as a Treatment for Pediatric Obesity

TypeinterventionalSponsorFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludRan2021 to 2023Enrolled30ConditionsInfant Obesity, Hepatic Steatosis, Metabolic Syndrome, Insulin ResistanceArmsStandard Care, Time restricted eating
NCT07262593 naterminatednot on this mapstarted 2024, after this paper: background citation

Family-Based Meal Timing for Cancer Prevention Among Native Hawaiian and Other Pacific Islanders: FAMTIME

TypeinterventionalSponsorUniversity of UtahRan2024 to 2024Enrolled2ConditionsCancer PreventionArmsTime Restricted Eating (TRE), Medically Tailored Meals (MTM)
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 6 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Pooled it
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  5. Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  6. Intermittent fasting and weight loss: Systematic review.Canadian family physician Medecin de famille canadien · 2020
    Pooled it
  7. Trial
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  10. Review
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Terra G ArnasonTerra G Arnason, Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK S7K 5E5, Canada.
Matthew W BowenTerra G Arnason, Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK S7K 5E5, Canada.
Kerry D MansellTerra G Arnason, Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK S7K 5E5, Canada.
University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the short-term biochemical effects and clinical tolerability of intermittent fasting (IF) in adults with type 2 diabetes mellitus (T2DM).

methodsWe describe a three-phase observational study (baseline 2 wk, intervention 2 wk, follow-up 2 wk) designed to determine the clinical, biochemical, and tolerability of IF in community-dwelling volunteer adults with T2DM. Biochemical, anthropometric, and physical activity measurements (using the Yale Physical Activity Survey) were taken at the end of each phase. Participants reported morning, afternoon and evening self-monitored blood glucose (SMBG) and fasting duration on a daily basis throughout all study stages, in addition to completing a remote food photography diary three times within each study phase. Fasting blood samples were collected on the final days of each study phase.

resultsAt baseline, the ten participants had a confirmed diagnosis of T2DM and were all taking metformin, and on average were obese [mean body mass index (BMI) 36.90 kg/m

conclusionThe results from this pilot study indicate that short-term daily IF may be a safe, tolerable, dietary intervention in T2DM patients that may improve key outcomes including body weight, fasting glucose and postprandial variability. These findings should be viewed as exploratory, and a larger, longer study is necessary to corroborate these findings.

Indexed as

Homeostasis model of assessment for insulin resistence indexIntermittent fastingRemote food photographySelf-monitored blood glucoseType 2 diabetes

Identifiers

PMID28465792
PMCPMC5394735
OpenAlexW2606075807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.