Evidence map›Paper›PMID 28465784›Full record

ArticleWorld journal of gastrointestinal endoscopy2017

Does deep sedation with propofol affect adenoma detection rates in average risk screening colonoscopy exams?

Selvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Joseph Ruiz, Richard Carlson, Katherine B Hagan, Jeffrey H Lee, William A Ross

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Selvi ThirumurthiSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Gottumukkala S RajuSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Mala PandeSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Joseph RuizSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Richard CarlsonSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Katherine B HaganSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Jeffrey H LeeSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
William A RossSelvi Thirumurthi, Gottumukkala S Raju, Mala Pande, Jeffrey H Lee, William A Ross, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
Creative Research Enterprises (United States) · USHospital Universitario Virgen Macarena · ESMito Saiseikai General Hospital · JPThe University of Texas MD Anderson Cancer Center · US

Funding

Susceptibility Markers for a Breast-Colon Cancer PhenotypeK07CA160753 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PANDE, MALA · 2012 to 2016
$603k
NCI NIH HHS K07 CA160753
6 · The paper itself

Abstract

aimTo determine the effect of sedation with propofol on adenoma detection rate (ADR) and cecal intubation rates (CIR) in average risk screening colonoscopies compared to moderate sedation.

methodsWe conducted a retrospective chart review of 2604 first-time average risk screening colonoscopies performed at MD Anderson Cancer Center from 2010-2013. ADR and CIR were calculated in each sedation group. Multivariable regression analysis was performed to adjust for potential confounders of age and body mass index (BMI).

resultsOne-third of the exams were done with propofol (

conclusionDeep sedation with propofol for screening colonoscopy did not significantly improve ADR or CIR in our population of average risk patients. While propofol may allow for safer sedation in certain patients (

Indexed as

Adenoma detection rateCecal intubation rateColonoscopyPropofolQuality metricsSedation

Identifiers

PMID28465784
PMCPMC5394724
OpenAlexW2607439145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.