ArticleMaedica2015
Predictors of in-Hospital Mortality of ST-Segment Elevation Myocardial Infarction Patients Undergoing Interventional Treatment. An Analysis of Data from the RO-STEMI Registry.
Article in Maedica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- The Hidden Burden of Depression in STEMI: Effects on Early Complications and 12-Month MACCE.Diagnostics (Basel, Switzerland) · 2026Article
- Evaluation of R2CHADS2, R2CHA2DS2-VASc, and R2CHA2DS2-VA Scores for the Prediction of In-Hospital Mortality in Patients with ST-Elevation Myocardial Infarction.Journal of clinical medicine · 2025Article
- Factors Associated with Mortality Risk in Patients with Cardiogenic Shock Post-ST-Elevation Myocardial Infarction: Insights from a Regional Centre in Northwest Romania.Medicina (Kaunas, Lithuania) · 2025Observational
- Sex Disparities in Ischemic Heart Disease Mortality in Europe.JACC. Advances · 2024Article
- Severe Left Ventricular Dysfunction Earlier after Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention: Predictors and In-Hospital Outcome- A Middle Eastern Tertiary Center Experience.Journal of the Saudi Heart Association · 2022Article
- Predictors of Mortality and Long-Term Outcome in Patients with Anterior STEMI: Results from a Single Center Study.Journal of clinical medicine · 2021Article
- Epidemiological Variation of Acute Myocardial Infarction Relevant to In-Hospital Outcomes-Tertiary Center Experience-Saudi Arabia.Journal of the Saudi Heart Association · 2020Article
- Peculiarities and Consequences of Different Angiographic Patterns of STEMI Patients Receiving Coronary Angiography Only: Data from a Large Primary PCI Registry.Emergency medicine international · 2020Article
- Article
- Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017.International journal of environmental research and public health · 2019Article
- Does Invasive Treatment Increase the Long-Term Survival of ST-Elevation Myocardial Infarction Patients with a History of Coronary Artery Bypass Graft Surgery?The journal of Tehran Heart Center · 2019Article
- Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre.Journal of interventional cardiology · 2019Observational
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundST-segment elevation myocardial infarction (STEMI) remains a leading cause of morbidity and mortality worldwide. Primary percutaneous coronary intervention (pPCI) is the preferred therapy for STEMI if it is done within 120 min from the first medical contact, by an experienced team in a high-volume center. The aim of this study was to assess the clinical characteristics and predictors of in-hospital mortality of patients with STEMI treated by percutaneous coronary interventions (PCIs).
methodsWe analyzed data from 15,076 STEMI patients enrolled in the RO-STEMI registry (ROmanian ST-Elevation Myocardial Infarction registry). Patients were divided into 2 groups: PCI (11.669; 77%) and conservative treated (3.407; 23%). PCI group includes both pPCI treated patients (84.3%), and patients undergoing rescue PCI (6.4%) and late PCI (9.3%).
resultsThe mean age of STEMI patients was 62.7+/-12.7 years. 70% were males. Patients treated by PCI were younger (61.4+/-12.2 versus 67.2+/-13.3, p< 0.0001) and more often men (80% versus 71%, p< 0.0001). They were less likely to have acute heart failure (Killip class II-IV) at admission (p< 0.0001). During admission, patients treated by PCI received more often dual antiplatelet therapy (97.6% versus 90.8%, p< 0.0001), statins (96.3% versus 87.5%, p< 0.0001), beta-blockers (83.8% versus 73.2%, p< 0.0001), and RAAS blockers (82.6% versus 66.4%, p< 0.0001). Overall in-hospital mortality was 7.1%: 4.1% in the PCI group and 15.7% in the conservative treated group. Multivariate analysis showed that, after adjusting for all clinical variables, Killip class II-IV at admission (OR: 9.2; 95%CI: 6.2-13.6; p< 0.0001), LVEF< 35% (OR: 3.8; 95%CI: 2.6-5.4; p< 0.0001), age older than 65 years (OR: 2.2; 95%CI: 1.5-3.2; p< 0.0001), and anterior location of myocardial infarction (OR: 2.1; 95% CI: 1.5-3; p< 0.0001) remained independent predictors for in-hospital mortality for STEMI patients treated interventionally.
conclusionAdvanced Killip class, depressed LVEF, advanced age, and anterior location were the most powerful independent predictors of in-hospital mortality in STEMI patients who underwent interventional treatment.
Identifiers
28465728PMC5394434W2976796633What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.