Evidence map›Paper›PMID 28465675›Full record

ReviewJournal of the International Society of Sports Nutrition2017

Dietary thiols in exercise: oxidative stress defence, exercise performance, and adaptation.

Yanita McLeay, Stephen Stannard, Stuart Houltham, Carlene Starck

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the International Society of Sports Nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 72 citations in OpenAlex.

  1. Trial
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  8. Article
  9. Phytochemical Analysis and Antioxidant Effects ofInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Impact ofFrontiers in microbiology · 2024
    Article
  12. Quercetin in Sports and Exercise: A review.International journal of exercise science · 2023
    Review
  13. CHeliyon · 2022
    Article
  14. Review
  15. Well-Trained Elders Have Antioxidant Responses and an Equal Magnitude of EIMD as Young Adults.International journal of environmental research and public health · 2022
    Article
  16. Article
  17. Article
  18. Effect ofFrontiers in microbiology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yanita McLeaySchool of Sport and Exercise, Massey University, Private Bag 11-222, Palmerston North, New Zealand.ORCID 0000-0002-9444-1653
Stephen StannardSchool of Sport and Exercise, Massey University, Private Bag 11-222, Palmerston North, New Zealand.
Stuart HoulthamSchool of Sport and Exercise, Massey University, Private Bag 11-222, Palmerston North, New Zealand.
Carlene StarckMassey Institute of Food Science and Technology, Massey University, Palmerston North, New Zealand.
Massey University · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endurance athletes are susceptible to cellular damage initiated by excessive levels of aerobic exercise-produced reactive oxygen species (ROS). Whilst ROS can contribute to the onset of fatigue, there is increasing evidence that they play a crucial role in exercise adaptations. The use of antioxidant supplements such as vitamin C and E in athletes is common; however, their ability to enhance performance and facilitate recovery is controversial, with many studies suggesting a blunting of training adaptations with supplementation. The up-regulation of endogenous antioxidant systems brought about by exercise training allows for greater tolerance to subsequent ROS, thus, athletes may benefit from increasing these systems through dietary thiol donors. Recent work has shown supplementation with a cysteine donor (N-acetylcysteine; NAC) improves antioxidant capacity by augmenting glutathione levels and reducing markers of oxidative stress, as well as ergogenic potential through association with delayed fatigue in numerous experimental models. However, the use of this, and other thiol donors may have adverse physiological effects. A recent discovery for the use of a thiol donor food source, keratin, to potentially enhance endogenous antioxidants may have important implications for endurance athletes hoping to enhance performance and recovery without blunting training adaptations.

Indexed as

Athletic PerformanceDietOxidative StressAdaptation, PhysiologicalAntioxidantsAthletesExerciseHumansPerformance-Enhancing SubstancesReactive Oxygen SpeciesSulfhydryl CompoundsAntioxidantsPerformance-Enhancing SubstancesReactive Oxygen SpeciesSulfhydryl CompoundsAntioxidantEnduranceThiol

Identifiers

PMID28465675
PMCPMC5408473
OpenAlexW2608623997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.