ArticleInternational journal of obesity (2005)2017
Central fat accretion and insulin sensitivity: differential relationships in parous and nulliparous women.
Article in International journal of obesity (2005), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Relationships Between Regional and Ectopic Adiposity and Insulin Sensitivity in Early and Late Pregnancy.Diabetes care · 2026Article
- Low-normal FT4 in early pregnancy as an independent risk factor for GDM: a large-scale retrospective cohort study.Frontiers in endocrinology · 2026Article
- Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus.Diabetology & metabolic syndrome · 2024Article
- Sarcopenia and Its Implications for Metabolic Health.Journal of obesity · 2019Review
- Association of adiponectin gene variants with idiopathic recurrent miscarriage according to obesity status: a case-control study.Journal of translational medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectivesChildbearing is associated with a disproportionate accumulation of visceral fat and an increased risk of metabolic disease. However, it is unknown whether the visceral fat accretion associated with pregnancy modifies a woman's risk for metabolic disease. The purpose of this study was to test whether the association between abdominal fat and insulin sensitivity differs by parity status in healthy overweight women. SUBJECTS/
methodsIntra-abdominal adipose tissue (IAAT) via CT, body composition by DXA, insulin sensitivity via intravenous glucose tolerance test and minimal model (S
resultsNulliparous women (n=98) were younger, had less IAAT and higher VO
conclusionsResults suggest that greater IAAT in parous women does not lead to greater insulin resistance; rather, transient insulin resistance during pregnancy may encourage intra-abdominal fat accumulation that is metabolically benign. This underscores the need to consider parity when assessing cardiometabolic risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.