Evidence map›Paper›PMID 28465440›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

High-density lipoprotein receptor SCARB1 is required for carotenoid coloration in birds.

Matthew B Toomey, Ricardo J Lopes, Pedro M Araújo, James D Johnson, Małgorzata A Gazda, Sandra Afonso, Paulo G Mota, Rebecca E Koch, Geoffrey E Hill, Joseph C Corbo and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

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  14. Widespread variation inbioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Role Analysis of theAnimals : an open access journal from MDPI · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew B ToomeyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110; mbtoomey@gmail.com jcorbo@pathology.wustl.edu miguel.carneiro@cibio.up.pt.ORCID 0000-0001-9184-197X
Ricardo J LopesCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.ORCID 0000-0003-2193-5107
Pedro M AraújoCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.
James D JohnsonDepartment of Biological Sciences, Auburn University, Auburn, AL 36849.
Małgorzata A GazdaCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.
Sandra AfonsoCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.
Paulo G MotaCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.
Rebecca E KochDepartment of Biological Sciences, Auburn University, Auburn, AL 36849.
Geoffrey E HillDepartment of Biological Sciences, Auburn University, Auburn, AL 36849.ORCID 0000-0001-8864-6495
Joseph C CorboDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110; mbtoomey@gmail.com jcorbo@pathology.wustl.edu miguel.carneiro@cibio.up.pt.
Miguel CarneiroCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal; mbtoomey@gmail.com jcorbo@pathology.wustl.edu miguel.carneiro@cibio.up.pt.

Funding

Research Training Program in the Vision SciencesT32EY013360 · NEI · WASHINGTON UNIVERSITY · PI SHIMING CHEN, Daniel Kerschensteiner · 2000 to 2026
$5.6M
CONVERTING BIPOLAR CELLS INTO RED-SHIFTED OPTOGENETIC SENSORS FOR RETINAL THERAPYR01EY024958 · NEI · WASHINGTON UNIVERSITY · PI CORBO, JOSEPH, FLANNERY, JOHN GERARD · 2015 to 2019
$2.2M
DECIPHERING THE MECHANISTIC BASIS OF INFRARED VISION FOR OPTOGENETIC APPLICATIONSR01EY026672 · NEI · WASHINGTON UNIVERSITY · PI CORBO, JOSEPH · 2016 to 2019
$1.4M
NEI NIH HHS R01 EY024958NEI NIH HHS R01 EY026672NEI NIH HHS T32 EY013360
6 · The paper itself

Abstract

Yellow, orange, and red coloration is a fundamental aspect of avian diversity and serves as an important signal in mate choice and aggressive interactions. This coloration is often produced through the deposition of diet-derived carotenoid pigments, yet the mechanisms of carotenoid uptake and transport are not well-understood. The white recessive breed of the common canary (

Indexed as

AnimalsCarotenoidsDietFeathersLipoproteins, HDLPigmentationReceptors, LipoproteinScavenger Receptors, Class BSongbirdsCarotenoidshigh density lipoprotein receptorsLipoproteins, HDLReceptors, LipoproteinScavenger Receptors, Class Bcarotenoidscolorationlipid metabolismSerinus canaria

Identifiers

PMID28465440
PMCPMC5441819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.