Evidence map›Paper›PMID 28465438›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm.

Nan-Peng Chen, Borhan Uddin, Robert Hardt, Wen Ding, Marko Panic, Ilaria Lucibello, Patricia Kammerer, Thomas Ruppert, Elmar Schiebel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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  16. The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nan-Peng ChenZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Borhan UddinZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Robert HardtZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Wen DingZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Marko PanicZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Ilaria LucibelloZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Patricia KammererMax Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Thomas RuppertZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany.
Elmar SchiebelZentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Deutsches Krebsforschungszentrum (DKFZ)-ZMBH Allianz, Universität Heidelberg, 69120 Heidelberg, Germany; e.schiebel@zmbh.uni-heidelberg.de.
German Cancer Research Center · DEMax Planck Institute of Biochemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CDC14 is an essential dual-specificity phosphatase that counteracts CDK1 activity during anaphase to promote mitotic exit in

Indexed as

Actinsbeta CateninCadherinsCell AdhesionCell Cycle ProteinsCell DivisionCell MovementCytoskeletal ProteinsHEK293 CellsHeLa CellsHumansPhosphoric Monoester HydrolasesPhosphorylationProtein Tyrosine PhosphatasesActinsbeta CateninCadherinsCDC14A protein, humanCell Cycle ProteinsCytoskeletal ProteinsLIMA1 protein, humanPhosphoric Monoester HydrolasesProtein Tyrosine Phosphatasesactin dynamicsCDC14eplin

Identifiers

PMID28465438
PMCPMC5441781
OpenAlexW2611344794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.