Evidence map›Paper›PMID 28465436›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Structural variants caused by

Lindsay M Payer, Jared P Steranka, Wan Rou Yang, Maria Kryatova, Sibyl Medabalimi, Daniel Ardeljan, Chunhong Liu, Jef D Boeke, Dimitri Avramopoulos, Kathleen H Burns

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. Article
  2. Article
  3. Extrachromosomal Circular DNA and Transposable Elements in Type 2 Diabetes.International journal of molecular sciences · 2025
    Review
  4. Direct identification ofbioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Review
  7. Transposons disrupt genomic stability and trigger cancers.Frontiers in cellular and infection microbiology · 2025
    Review
  8. Article
  9. Review
  10. Epigenomic insights into common human disease pathology.Cellular and molecular life sciences : CMLS · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lindsay M PayerDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205; kburns@jhmi.edu lhorvat1@jhmi.edu jef.boeke@nyumc.org.
Jared P SterankaDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Wan Rou YangDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Maria KryatovaDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Sibyl MedabalimiDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Daniel ArdeljanDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Chunhong LiuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Jef D BoekeMcKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205; kburns@jhmi.edu lhorvat1@jhmi.edu jef.boeke@nyumc.org.ORCID 0000-0001-5322-4946
Dimitri AvramopoulosMcKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Kathleen H BurnsDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205; kburns@jhmi.edu lhorvat1@jhmi.edu jef.boeke@nyumc.org.ORCID 0000-0003-1620-3761

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007309 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 1985 to 2019
$43.2M
Somatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?P01AG051449 · NIA · BROWN UNIVERSITY · PI Jef D BOEKE · 2016 to 2026
$30.4M
TRAINING IN AREAS FUNDAMENTAL TO CANCER RESEARCHT32CA009110 · NCI · JOHNS HOPKINS UNIVERSITY · PI MATUNIS, MICHAEL J., WEERARATNA, ASHANI T · 1985 to 2025
$13.1M
Predoctoral Training Program in Human GeneticsT32GM007814 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VALLE, DAVID · 1985 to 2021
$10.6M
Training CoreP50GM107632 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BOEKE, JEF D · 2013 to 2017
$10.0M
TRAINING PROGRAM IN HEMATOLOGYT32HL007525 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ROBERT A BRODSKY · 1985 to 2026
$6.2M
Transposon Insertion Polymorphisms in Predispositions to Hematopoietic NeoplasiaR01CA163705 · NCI · JOHNS HOPKINS UNIVERSITY · PI BURNS, KATHLEEN H · 2013 to 2017
$1.7M
Mouse Models of Functional Insertion PolymorphismsR01GM103999 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BURNS, KATHLEEN H · 2013 to 2016
$1.2M
NCI NIH HHS R01 CA163705NCI NIH HHS T32 CA009110NHLBI NIH HHS T32 HL007525NIA NIH HHS P01 AG051449NIGMS NIH HHS P50 GM107632NIGMS NIH HHS R01 GM103999NIGMS NIH HHS T32 GM007309NIGMS NIH HHS T32 GM007814
6 · The paper itself

Abstract

Interspersed repeat sequences comprise much of our DNA, although their functional effects are poorly understood. The most commonly occurring repeat is the

Indexed as

Alu ElementsCase-Control StudiesDiseaseGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansLinkage DisequilibriumPolymorphism, Single NucleotideAlucausative variantGWASinterspersed repeatsstructural variant

Identifiers

PMID28465436
PMCPMC5441760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.