Evidence map›Paper›PMID 28465299›Full record

SynthesisJournal of the American Heart Association2017

Risk for Incident Heart Failure: A Subject-Level Meta-Analysis From the Heart "OMics" in AGEing (HOMAGE) Study.

Lotte Jacobs, Ljupcho Efremov, João Pedro Ferreira, Lutgarde Thijs, Wen-Yi Yang, Zhen-Yu Zhang, Roberto Latini, Serge Masson, Nera Agabiti, Peter Sever and 8 more

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Diagnostic Tests for Stage B Heart Failure.Current cardiology reports · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Cancer and Heart Failure: Dangerous Liaisons.Journal of cardiovascular development and disease · 2024
    Review
  9. Observational
  10. Review
  11. Article
  12. Article
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 5 countries.

Lotte JacobsResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Ljupcho EfremovResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
João Pedro FerreiraINSERM, Centre d'Investigations Cliniques Plurithe'matique 1433, INSERM U1116, CHRU de Nancy, F-CRIN INI-CRCT, Universite' de Lorraine, Nancy, France.
Lutgarde ThijsResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Wen-Yi YangResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Zhen-Yu ZhangResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Roberto LatiniDepartment of Cardiovascular Research, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
Serge MassonDepartment of Cardiovascular Research, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
Nera AgabitiDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Peter SeverInternational Centre for Circulatory Health, Imperial College London, London, United Kingdom.
Christian DellesInstitute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, United Kingdom.
Naveed SattarInstitute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, United Kingdom.
Javed ButlerDivision of Cardiology, Stony Brook University, Stony Brook, NY.
John G F ClelandNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Tatiana KuznetsovaResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Jan A StaessenResearch Unit of Hypertension and Cardiovascular Epidemiology, Studies Coordinating Centre, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium jan.staessen@med.kuleuven.be.
Faiez ZannadINSERM, Centre d'Investigations Cliniques Plurithe'matique 1433, INSERM U1116, CHRU de Nancy, F-CRIN INI-CRCT, Universite' de Lorraine, Nancy, France.
Heart “OMics” in AGEing (HOMAGE) investigators
KU Leuven · BEIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Glasgow · GBFrench Clinical Research Infrastructure Network · FRImperial College London · GBRegional Health · USStony Brook University · USUniversité de Lorraine · FRUniversity of Hull · GB

Funding

European Research Council 294713
6 · The paper itself

Abstract

backgroundTo address the need for personalized prevention, we conducted a subject-level meta-analysis within the framework of the Heart "OMics" in AGEing (HOMAGE) study to develop a risk prediction model for heart failure (HF) based on routinely available clinical measurements. METHODS AND

resultsThree studies with elderly persons (Health Aging and Body Composition [Health ABC],

conclusionsSimple measurements allow reliable estimation of the short-term HF risk in populations and patients. The risk model may aid in risk stratification and future HF prevention strategies.

Indexed as

AgingDecision Support TechniquesAdultAgedAged, 80 and overAge FactorsArea Under CurveBiomarkersBlood PressureChi-Square DistributionComorbidityFemaleGeriatric AssessmentHeart FailureHeart RateHospitalizationBiomarkersheart failuremeta‐analysisrisk factorrisk prediction

Identifiers

PMID28465299
PMCPMC5524083
OpenAlexW2611251542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.