ArticleAdvanced healthcare materials2017
Extrusion Bioprinting of Shear-Thinning Gelatin Methacryloyl Bioinks.
Article in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 170 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
170 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Candidate Bioinks for Extrusion 3D Bioprinting-A Systematic Review of the Literature.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Exploring the role of 4D printing materials, techniques, and characteristics for personalized oncology.Translational oncology · 2026Review
- Self-Growing and Mechanically Tunable Living Materials withACS applied polymer materials · 2026Article
- Computational approaches in bioprinting processes.Nature reviews bioengineering · 2026Article
- Biomaterial Strategies for Three-Dimensional Bioprinting and Drug Delivery Application.Materials (Basel, Switzerland) · 2026Review
- Modeling of Biomechanical and Functional Parameters of Hydrogel-Cell Composites Fabricated by 3D Bioprinting Using AI-Supported Approach.Materials (Basel, Switzerland) · 2026Article
- Feasible Regions of Nozzle Temperature, Extrusion Pressure, and Printing Speed in Extrusion-Based Printing Using a Sodium Alginate-Carboxymethylcellulose-Collagen I Bioink.Biomimetics (Basel, Switzerland) · 2026Article
- Unconventional bioprinting modalities for advanced tissue biofabrication.Biomaterials · 2026Review
- Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting.Advanced healthcare materials · 2026Article
- Advances and Challenges in 3D Bioprinting of Cartilage Organoids: From Material Innovation to Functional Regeneration.International journal of nanomedicine · 2026Review
- Pediatric physeal repair: from immune-angiogenic-osteogenic coupling to zonal biomimetic scaffolds.Frontiers in cell and developmental biology · 2026Review
- Cell Behavior and Complex Mechanical Properties of 3D Printed Cell-Laden Alginate-Gelatin Macroporous Mesostructures.Macromolecular bioscience · 2025Article
- Cast-Molded Channelized Hydrogel Scaffolds With Stereolithography-Printed Templates.Biotechnology and bioengineering · 2025Article
- Integrated bioprinting of trachea-like structures based on tissue-specific bioink.Materials today. Bio · 2025Article
- Novel GelMA/GelMA-AEMA Hydrogel Blend with Enhanced Printability as a Carrier for iPSC-Derived Chondrocytes In Vitro.Gels (Basel, Switzerland) · 2025Article
- 3D Printing of Conducting Polymer Hydrogels for Electrostimulation-Assisted Tissue Engineering.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Additive Manufacturing of Lignocellulosic Aerogels from Minimally Processed Waste Streams.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Photocrosslinkable Kidney Decellularized Extracellular Matrix-Based Bioink for 3D Bioprinting.Advanced healthcare materials · 2025Article
- 3D Printing β-TCP-laden GelMA/Alginate Interpenetrating-Polymer-Network Biomaterial Inks for Bone Tissue Engineering.Bioprinting (Amsterdam, Netherlands) · 2025Article
- Recent Advances in Handheld and Robotic Bioprinting Approach for Tissue Engineering.Advanced materials technologies · 2025Article
110 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly in the case of extrusion-based bioprinting. Herein, this paper reports a novel strategy to directly bioprint cell-laden gelatin methacryloyl (GelMA) constructs using bioinks of GelMA physical gels (GPGs) achieved through a simple cooling process. Attributed to their shear-thinning and self-healing properties, the GPG bioinks can retain the shape and form integral structures after deposition, allowing for subsequent UV crosslinking for permanent stabilization. This paper shows the structural fidelity by bioprinting various 3D structures that are typically challenging to fabricate using conventional bioinks under extrusion modes. Moreover, the use of the GPG bioinks enables direct bioprinting of highly porous and soft constructs at relatively low concentrations (down to 3%) of GelMA. It is also demonstrated that the bioprinted constructs not only permit cell survival but also enhance cell proliferation as well as spreading at lower concentrations of the GPG bioinks. It is believed that such a strategy of bioprinting will provide many opportunities in convenient fabrication of 3D cell-laden constructs for applications in tissue engineering, regenerative medicine, and pharmaceutical screening.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.