Evidence map›Paper›PMID 28464542›Full record

ArticleHead & neck2017

Quantitative pretreatment CT volumetry: Association with oncologic outcomes in patients with T4a squamous carcinoma of the larynx.

Jay C Shiao, Abdallah S R Mohamed, Jay A Messer, Katherine A Hutcheson, Jason M Johnson, Heiko Enderling, Mona Kamal, Benjamin W Warren, Brian Pham, William H Morrison and 15 more

Open access · greenAbstract read
In one paragraph

Article in Head & neck, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Tumor volume as a prognostic factor of locally advanced laryngeal cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  4. [Pathologic tumor volume predicting survival outcomes of patients with local advanced glottic carcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article
  5. Review
  6. Laser debulking or tracheotomy in airway management prior to total laryngectomy for T4a laryngeal cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 4 institutions in 2 countries.

Jay C ShiaoDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Abdallah S R MohamedDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-2064-7613
Jay A MesserDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Katherine A HutchesonDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-3710-5706
Jason M JohnsonDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Heiko EnderlingIntegrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Mona KamalDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Benjamin W WarrenDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Brian PhamDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
William H MorrisonDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Mark E ZafereoDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Amy C HesselDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Stephen Y LaiDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Merril S KiesDepartment of Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Renata FerrarottoDepartment of Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Adam S GardenDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Donald F SchomerDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
G Brandon GunnDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Jack PhanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Steven J FrankDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Beth M BeadleDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Randal S WeberDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Jan S LewinDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David I RosenthalDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Clifton D FullerDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-5264-3994
The University of Texas MD Anderson Cancer Center · USAin Shams University · EGMoffitt Cancer Center · USTexas Medical Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Targeting the p53 pathway for reversal of oral premalignancyP50CA097007 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MYERS, JEFFREY NICHOLAS · 2002 to 2012
$26.1M
Paul Calabresi Clinical Oncology AwardK12CA088084 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI David S. Hong, Scott Kopetz · 2000 to 2026
$14.0M
Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Establish Objective Clinical Outcome Measures for Mandibular OsteoradionecrosisR01DE025248 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LAI, STEPHEN Y · 2016 to 2020
$2.9M
SMART-ACT: Spatial Methodologic Approaches for Risk Assessment and Therapeutic Adaptation in Cancer TreatmentR01CA214825 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$1.1M
Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Establish Objective Clinical Outcome Measures for Mandibular OsteoradionecrosisR56DE025248 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LAI, STEPHEN Y · 2015 to 2015
$470k
NCI NIH HHS K12 CA088084NCI NIH HHS L30 CA136381NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA097007NCI NIH HHS R01 CA214825NIDCR NIH HHS R01 DE025248NIDCR NIH HHS R56 DE025248
6 · The paper itself

Abstract

backgroundThe purpose of this study was to determine the impact of CT-determined pretreatment primary tumor volume on survival and disease control in T4a laryngeal squamous cell carcinoma (SCC).

methodsWe retrospectively reviewed 124 patients with T4a laryngeal cancer from 2000-2011. Tumor volume measurements were collected and correlated with outcomes.

resultsFive-year overall survival (OS) for patients with tumor volume ≥21 cm

conclusionPretreatment CT-based tumor volume is an independent prognostic factor of outcomes in T4a laryngeal cancer.

Indexed as

Tumor BurdenAdultAgedAged, 80 and overCarcinoma, Squamous CellCombined Modality TherapyCone-Beam Computed TomographyFemaleHumansLaryngeal NeoplasmsLaryngectomyLarynxMaleMiddle AgedNeoplasm StagingPrognosisoutcomesradiotherapysurvivalT4atumorvolumevolumetry

Identifiers

PMID28464542
PMCPMC5511768
OpenAlexW2611796082

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.