Evidence map›Paper›PMID 28463603›Full record

ReviewTissue engineering. Part A2017

Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids for Bone Tissue Engineering and Regenerative Medicine<sup/>.

Kyungsup Shin, Timothy Acri, Sean Geary, Aliasger K Salem

Abstract readReview
In one paragraph

Review in Tissue engineering. Part A, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Review
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  15. Biomineral-Based Composite Materials in Regenerative Medicine.International journal of molecular sciences · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. Active and Passive Mineralization of Bio-GideJournal of functional biomaterials · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kyungsup Shin1 Department of Orthodontics, College of Dentistry and Dental Clinics, University of Iowa , Iowa City, Iowa.
Timothy Acri2 Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa , Iowa City, Iowa.
Sean Geary2 Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa , Iowa City, Iowa.
Aliasger K Salem2 Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa , Iowa City, Iowa.

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Development of synthetic biomaterials imbued with inorganic and organic characteristics of natural bone that are capable of promoting effective bone tissue regeneration is an ongoing goal of regenerative medicine. Calcium phosphate (CaP) has been predominantly utilized to mimic the inorganic components of bone, such as calcium hydroxyapatite, due to its intrinsic bioactivity and osteoconductivity. CaP-based materials can be further engineered to promote osteoinductivity through the incorporation of osteogenic biomolecules. In this study, we briefly describe the microstructure and the process of natural bone mineralization and introduce various methods for coating CaP onto biomaterial surfaces. In particular, we summarize the advantages and current progress of biomimetic surface-mineralizing processes using simulated body fluids for coating bone-like carbonated apatite onto various material surfaces such as metals, ceramics, and polymers. The osteoinductive effects of integrating biomolecules such as proteins, growth factors, and genes into the mineral coatings are also discussed.

Indexed as

Calcification, PhysiologicRegenerative MedicineAnimalsBiocompatible MaterialsBiomimeticsBody FluidsBone and BonesHumansTissue EngineeringBiocompatible Materialsbonebone tissue engineeringcalcium phosphatepolymer scaffoldssimulated body fluids

Identifiers

PMID28463603
PMCPMC5653095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.