Evidence map›Paper›PMID 28463543›Full record

ReviewSmall GTPases2018

Roles for RAB24 in autophagy and disease.

Päivi Ylä-Anttila, Eeva-Liisa Eskelinen

Open access · bronzeAbstract readReview
In one paragraph

Review in Small GTPases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Genes · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Modulation ofAutophagy · 2023
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy.Matrix biology : journal of the International Society for Matrix Biology · 2021
    Article
  15. Proteoglycan-driven Autophagy: A Nutrient-independent Mechanism to Control Intracellular Catabolism.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020
    Review
  16. Article
  17. Rab GTPases in Osteoclastic Bone Resorption and Autophagy.International journal of molecular sciences · 2020
    Review
  18. Article
  19. Catabolic degradation of endothelial VEGFA via autophagy.The Journal of biological chemistry · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Päivi Ylä-Anttilaa Department of Biosciences , University of Helsinki , Helsinki , Finland.
Eeva-Liisa Eskelinena Department of Biosciences , University of Helsinki , Helsinki , Finland.ORCID 0000-0003-0006-7785
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is an evolutionarily conserved degradation pathway for cells to maintain homeostasis, produce energy, degrade misfolded proteins and damaged organelles, and fight against intracellular pathogens. The process of autophagy entails the isolation of cytoplasmic cargo into double membrane bound autophagosomes that undergo maturation by fusion with endosomes and lysosomes to obtain degradation capacity. RAB proteins regulate intracellular vesicle trafficking events including autophagy. RAB24 is an atypical RAB protein that is required for the clearance of late autophagic vacuoles under basal conditions. RAB24 has also been connected to several diseases including ataxia, cancer and tuberculosis. This review gives a short summary on autophagy and RAB proteins, and an overview on the current knowledge on the roles of RAB24 in autophagy and disease.

Indexed as

AutophagyDiseaseAnimalsEndosomesHumansMembrane Fusionrab GTP-Binding Proteinsrab GTP-Binding Proteinsataxiaautophagyhepatocellular carcinomaRAB24RAB proteins

Identifiers

PMID28463543
PMCPMC5902223
OpenAlexW2611232600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.