Evidence map›Paper›PMID 28462586›Full record

ArticleBrain connectivity2017

Infraslow Electroencephalographic and Dynamic Resting State Network Activity.

Joshua K Grooms, Garth J Thompson, Wen-Ju Pan, Jacob Billings, Eric H Schumacher, Charles M Epstein, Shella D Keilholz

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Brain connectivity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 84 citations in OpenAlex.

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  13. Hemodynamic cortical ripples through cyclicity analysis.Network neuroscience (Cambridge, Mass.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joshua K Grooms1 Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, Georgia .
Garth J Thompson2 Magnetic Resonance Research Center (MRRC) and Radiology and Biomedical Imaging, Yale University , New Haven, Connecticut.
Wen-Ju Pan1 Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, Georgia .
Jacob Billings3 Department of Neuroscience, Emory University , Atlanta, Georgia .
Eric H Schumacher4 Department of Psychology, Georgia Institute of Technology , Atlanta, Georgia .
Charles M Epstein5 Department of Neurology, Emory University School of Medicine , Atlanta, Georgia .
Shella D Keilholz1 Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, Georgia .
Emory University · USGeorgia Institute of Technology · US

Funding

Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
NIDA NIH HHS T32 DA022975
6 · The paper itself

Abstract

A number of studies have linked the blood oxygenation level dependent (BOLD) signal to electroencephalographic (EEG) signals in traditional frequency bands (δ, θ, α, β, and γ), but the relationship between BOLD and its direct frequency correlates in the infraslow band (<1 Hz) has been little studied. Previously, work in rodents showed that infraslow local field potentials play a role in functional connectivity, particularly in the dynamic organization of large-scale networks. To examine the relationship between infraslow activity and network dynamics in humans, direct current (DC) EEG and resting state magnetic resonance imaging data were acquired simultaneously. The DC EEG signals were correlated with the BOLD signal in patterns that resembled resting state networks. Subsequent dynamic analysis showed that the correlation between DC EEG and the BOLD signal varied substantially over time, even within individual subjects. The variation in DC EEG appears to reflect the time-varying contribution of different resting state networks. Furthermore, some of the patterns of DC EEG and BOLD correlation are consistent with previous work demonstrating quasiperiodic spatiotemporal patterns of large-scale network activity in resting state. These findings demonstrate that infraslow electrical activity is linked to BOLD fluctuations in humans and that it may provide a basis for large-scale organization comparable to that observed in animal studies.

Indexed as

ElectroencephalographyMagnetic Resonance ImagingAdolescentAdultAlgorithmsBlood Flow VelocityBrainBrain MappingCerebrovascular CirculationFemaleHumansImage Interpretation, Computer-AssistedMaleNerve NetOximetryOxygenOxygenDC-EEGfunctional connectivityinfraslowresting state MRIsliding window correlation

Identifiers

PMID28462586
PMCPMC5510044
OpenAlexW2611583363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.