Evidence map›Paper›PMID 28462378›Full record

ReviewCellular and molecular gastroenterology and hepatology2017

Genomics, Endoscopy, and Control of Gastroesophageal Cancers: A Perspective.

Brian J Reid

Open access · goldAbstract readReview
In one paragraph

Review in Cellular and molecular gastroenterology and hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019
    Article
  4. Association of sporadic and familial Barrett's esophagus with breast cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2018
    Article
  5. Early Diagnosis of Gastroesophageal Cancers and the Cytosponge: A Work in Progress.Cellular and molecular gastroenterology and hepatology · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Brian J ReidDivisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
University of Washington · US

Funding

PHYLOGENIES of Barrett's Esophagus LineagesP01CA091955 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY · 2002 to 2019
$35.9M
(PQA1) Aspirin and Inflammation: Mutations, Genes, Pathways and PreventionR01CA179949 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LI, XIAOHONG, REID, BRIAN J · 2013 to 2016
$1.9M
NCI NIH HHS P01 CA091955NCI NIH HHS R01 CA179949
6 · The paper itself

Abstract

In The Cancer Genome Atlas the goals were to define how to treat advanced cancers with targeted therapy. However, the challenges facing cancer interception for early detection and prevention include length bias in which current screening and surveillance approaches frequently miss rapidly progressing cancers that then present at advanced stages in the clinic with symptoms (underdiagnosis). In contrast, many early detection strategies detect benign conditions that may never progress to cancer during a lifetime, and the patient dies of unrelated causes (overdiagnosis). This challenge to cancer interception is believed to be due to the speed at which the neoplasm evolves, called

Indexed as

Barrett's EsophagusBE, Barrett’s esophagusBiomarkersChromosome AberrationsCIN, chromosome instabilityEA, esophageal adenocarcinomaEsophageal NeoplasmsGastroesophageal RefluxGenomic InstabilityGenomicsGI, gastrointestinalPCGA, pre-cancer genome atlasStomachTCGA, The Cancer Genome AtlasWGD, whole genome doubling

Identifiers

PMID28462378
PMCPMC5404103
OpenAlexW2591382756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.