Evidence map›Paper›PMID 28462169›Full record

ArticleUrology case reports2017

Managing Renal Cell Carcinoma Associated Paraneoplastic Syndrome with Nephron-sparing Surgery in a Patient with von Hippel-Lindau.

John M DiBianco, Julie Y An, Sally Tanakchi, Zachary Stanik, Aidan McGowan, Mahir Maruf, Abhinav Sidana, Amit Lodha Jain, Akhil Muthigi, Arvin K George and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

John M DiBiancoSchool of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
Julie Y AnUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Sally TanakchiLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Zachary StanikUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Aidan McGowanUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Mahir MarufUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Abhinav SidanaUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Amit Lodha JainUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Akhil MuthigiUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Arvin K GeorgeUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Christopher BayneSchool of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
W Marston LinehanUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Shawna L BoyleUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
Adam R MetwalliUrologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bldg. 10, Hatfield Clinical Research Center, Rm 2 W-3952 10 Center Drive MSC 1210, 20892-1210, Bethesda, MD, USA.
National Cancer Institute · USCenter for Cancer Research · USGeorge Washington University · USNational Institutes of Health · US

Funding

Clinical Nursing and Data Management CoreZIDBC011089 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LINEHAN, WILLIAM MARSTON · 2009 to 2025
$17.4M
6 · The paper itself

Abstract

A patient with germline von Hippel-Lindau (VHL) gene alteration and history of multiple tumors present with classical paraneoplastic syndrome (PNS) associated with renal cell carcinoma (RCC). She underwent open nephron sparing surgery with resolution of symptoms. She remained without recurrence of RCC for the initial 2 years of her follow-up. To the best of our knowledge, this case represents the first in which PNS was specifically resolved using a partial nephrectomy in a patient with VHL. This case report provides initial evidence for the potential role of nephron sparing surgery in the management of paraneoplastic symptoms associated with hereditary RCC.

Indexed as

OncologyParaneoplasticPartial nephrectomyPNS, Paraneoplastic syndromeRCCRCC, Renal cell carcinomaVHLVHL, von Hippel-Lindau disease

Identifiers

PMID28462169
PMCPMC5408158
OpenAlexW2609117558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.