Evidence map›Paper›PMID 28462147›Full record

ReviewIntegrative medicine research2017

Shridhar C Ghagane, Sridevi I Puranik, Vijay M Kumbar, Rajendra B Nerli, Sunil S Jalalpure, Murigendra B Hiremath, Shivayogeeswar Neelagund, Ravindranath Aladakatti

Open access · goldAbstract readReview
In one paragraph

Review in Integrative medicine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Phytochemical Analysis and Antioxidant Activities ofAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. 3 Biotech · 2023
    Article
  14. Biogenic Synthesis of Zinc Oxide Nanoparticles UsingPlants (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Shridhar C GhaganeDepartment of Biotechnology and Microbiology, Karnatak University, Dharwad, India.
Sridevi I PuranikDepartment of Biotechnology and Microbiology, Karnatak University, Dharwad, India.
Vijay M KumbarDr. Prabhakar Kore Basic Science Research Center, KLE University, Belagavi, India.
Rajendra B NerliDepartment of Urology, KLES Kidney Foundation, KLES Dr. Prabhakar Kore Hospital & Medical Research Center, Belagavi, India.
Sunil S JalalpureDr. Prabhakar Kore Basic Science Research Center, KLE University, Belagavi, India.
Murigendra B HiremathDepartment of Biotechnology and Microbiology, Karnatak University, Dharwad, India.
Shivayogeeswar NeelagundDepartment of Biochemistry, Kuvempu university, Shimoga, India.
Ravindranath AladakattiCentral Animal Facility, Indian Institute of Science, Bangalore, India.
Karnatak University · INKLE University · INIndian Institute of Science Bangalore · INKLE Society Hospital · INKuvempu University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine the phytochemical constituents, antioxidant, and anticancer activities of

methodsLeaf sample was subjected to Soxhlet extraction method with increasing polarity of solvents, namely, chloroform, ethyl acetate, methanol, ethanol, and aqueous. Phytochemical screening was done using different biochemical tests. Quantitative analysis for phenol was determined by Folin-Ciocalteu reagent method. The antioxidant activity was tested using 2,2-diphenyl-1-picrylhydrazyl, ferric ion reducing power assay, and phosphomolybdenum assay.

resultsPhytochemical screening confirmed the presence of phyto-constituents like alkaloids, flavonoids, glycosides, phenols, lignins, saponins, sterols, tannins, anthraquinone, and reducing sugar. Methanol and ethanol extracts exhibited higher phenolic content as compare to aqueous extract. Antioxidant capacities were shown highest in methanol and ethanol extracts based on the test performed. The methanol and ethanol leaf extracts were found to be selectively cytotoxic

conclusionThe results indicate that

Indexed as

anticancerantioxidantLeea indicaphytochemicalprostate cancer

Identifiers

PMID28462147
PMCPMC5395687
OpenAlexW2578798757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.