ReviewIntegrative medicine research2016
High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training.
Review in Integrative medicine research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Yoga interventions and randomized controlled trials: key issues and the centered impact on sedentary lifestyle-associated cardiometabolic disorders.Frontiers in clinical diabetes and healthcare · 2026Pooled it
- Impact of exercise dosages based on American College of Sports Medicine recommendations on lipid metabolism in patients after PCI: a systematic review and meta-analysis of randomized controlled trials.Lipids in health and disease · 2024Pooled it
- Extra Virgin Olive Oil Prevents the Age-Related Shifts of the Distribution of HDL Subclasses and Improves Their Functionality.Nutrients · 2021Trial
- Association Between Dietary Patterns and Lifestyle Habits with Vascular Inflammatory Responses in Individuals with Hypertension Living in PMDiseases (Basel, Switzerland) · 2025Article
- Effect of Resistance Training on Older Adults with Sarcopenic Obesity: A Comprehensive Systematic Review and Meta-Analysis of Blood Biomarkers, Functionality, and Body Composition.Nursing reports (Pavia, Italy) · 2025Review
- Exercise: Just What the Doctor Ordered, But Why? Elucidating Mechanisms for Women's Increased High-Density Lipoprotein Benefit From Exercise and for the Health ABC Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Article
- Risk Factors for Pelvic Organ Prolapse: Wide-Angled Mendelian Randomization Analysis.International urogynecology journal · 2024Article
- The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023Review
- Dietary diversity in primary schoolchildren of south-central Côte d'Ivoire and risk factors for non-communicable diseases.BMC pediatrics · 2022Article
- Protective cardiovascular benefits of exercise training as measured by circulating endothelial cells and high-density lipoprotein in adults.Journal of Taibah University Medical Sciences · 2022Article
- Physical inactivity level and lipid profile in traditional communities in the Legal Amazon: a cross-sectional study : Physical inactivity level in the Legal Amazon.BMC public health · 2022Article
- Combined Effects of High-Intensity Aerobic Exercise Training andFrontiers in endocrinology · 2022Article
- HDL Dysfunctionality: Clinical Relevance of Quality Rather Than Quantity.Biomedicines · 2021Review
- High atherogenic index of plasma and cardiovascular risk factors among Ghanaian breast cancer patients.Experimental biology and medicine (Maywood, N.J.) · 2020Article
- Identification ofRSC medicinal chemistry · 2020Article
- Novel Invasive and Noninvasive Cardiac-Specific Biomarkers in Obesity and Cardiovascular Diseases.Metabolic syndrome and related disorders · 2020Review
- Social Integration, Daily Discrimination, and Biological Markers of Health in Mid- and Later Life: Does Self-Esteem Play an Intermediary Role?Innovation in aging · 2020Article
- High Incidence of Diabetes in People with Extremely High High-Density Lipoprotein Cholesterol: Results of the Kanagawa Investigation of Total Checkup Data from the National Database-1 (KITCHEN-1).Journal of clinical medicine · 2019Article
- Impact of Successful Weight Loss Maintenance on Serum Lipids and Glucose Concentrations of Previous Participants of a Weight Loss Programme in Accra, Ghana.Journal of nutrition and metabolism · 2019Article
- Oxidative Stress and Inflammation, Key Targets of Atherosclerotic Plaque Progression and Vulnerability: Potential Impact of Physical Activity.Sports medicine (Auckland, N.Z.) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Decreases in high-density lipoprotein cholesterol (HDL-C) levels are associated with an increased risk of coronary artery disease (CAD), whereas increased HDL-C levels are related to a decreased risk of CAD and myocardial infarction. Although HDL prevents the oxidation of low-density lipoprotein under normal conditions, it triggers a structural change, inhibiting antiarteriosclerotic and anti-inflammatory functions, under pathological conditions such as oxidative stress, inflammation, and diabetes. HDL can transform into various structures based on the quantitative reduction and deformation of apolipoprotein A1 and is the primary cause of increased levels of dysfunctional HDL, which can lead to an increased risk of CAD. Therefore, analyzing the structure and components of HDL rather than HDL-C after the application of an exercise training program may be useful for understanding the effects of HDL.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.