Evidence map›Paper›PMID 28462109›Full record

ArticleIntegrative medicine research2016

Simultaneous determination of nine bioactive compounds in Yijin-tang via high-performance liquid chromatography and liquid chromatography-electrospray ionization-mass spectrometry.

Hye Jin Yang, Nam-Hui Yim, Kwang Jin Lee, Min Jung Gu, Bohyoung Lee, Youn-Hwan Hwang, Jin Yeul Ma

Abstract read
In one paragraph

Article in Integrative medicine research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hye Jin YangKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Nam-Hui YimKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Kwang Jin LeeKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Min Jung GuKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Bohyoung LeeKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Youn-Hwan HwangKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.
Jin Yeul MaKM Application Center, Korea Institute of Oriental Medicine, Daegu, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundYijin-tang (YJ) has been used traditionally for the treatment of cardiovascular conditions, nausea, vomiting, gastroduodenal ulcers, and chronic gastritis. In this study, a simple and sensitive high-performance liquid chromatography (HPLC) method was developed for the quantitation of nine bioactive compounds in YJ: homogentisic acid, liquiritin, naringin, hesperidin, neohesperidin, liquiritigenin, glycyrrhizin, 6-gingerol, and pachymic acid.

methodsChromatographic separation of the analytes was achieved on an RS Tech C

resultsCalibration curves for all analytes showed good linearity (R

conclusionThis validated HPLC method was applied to qualitative and quantitative analyses of nine bioactive compounds in YJ and fermented YJ, and may be a useful tool for the quality control of YJ.

Indexed as

HPLC-DADLC/MSsimultaneous determinationvalidationYijin-tang

Identifiers

PMID28462109
PMCPMC5381425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.