ArticlePeerJ2017
Differential transcript profile of inhibitors with potential anti-venom role in the liver of juvenile and adult
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Genome of venomous caterpillarProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Proteomics and life-history variability of Endogenous Phospholipases A2 Inhibitors (PLIs) in Bothrops jararaca plasma.PloS one · 2024Article
- Comparative compositional and functional analyses of Bothrops moojeni specimens reveal several individual variations.PloS one · 2019Article
- Purification and characterization of the first γ-phospholipase inhibitor (γPLI) from Bothrops jararaca snake serum.PloS one · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSnakes belonging to the
methodsIn order to identify anti-venom molecules, we construct a cDNA library from the liver of
resultsThe results revealed a 30-fold increase of gamma-phospholipase A DISCUSSION: The results suggest the up-regulation of different inhibitors observed in the adult snakes might be a physiological adaptation to the recurrent contact with their own and even other snake's venoms throughout its lifespan. This is the first comparative analysis of ontogenetic variation of expression profiles of plasmatic proteins with potential anti-venom activities of the venomous snake
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Registered trials
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