ArticleCentral European journal of urology2017
Is overactive bladder in the female surgically curable by ligament repair?
Article in Central European journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- The Interplay Between Chronic Pelvic Pain and Pelvic Organ Prolapse.International urogynecology journal · 2025Pooled it
- A gynecological perspective of interstitial cystitis/bladder pain syndrome may offer cure in selected cases.Central European journal of urology · 2022Trial
- Comparison of Postoperative Functional Recovery and Anatomical Restoration in Patients with Pelvic Organ Prolapse Undergoing Three Types of Apical Suspension Techniques: A Retrospective Study.International urogynecology journal · 2026Article
- Effect of vNOTES hysterectomy with uterosacral ligament suspension on overactive bladder symptoms in patients with pelvic organ prolapse: a retrospective cohort study.Turkish journal of medical sciences · 2026Article
- Laparoscopic lateral suspension combined with uterosacral ligament folding and shortening versus laparoscopic sacrocolpopexy for the treatment of pelvic organ prolapse: a retrospective cohort study.Frontiers in medicine · 2025Article
- A Critical Examination of Ligamentous Pathogenesis of Bladder Pain/Lower Urinary Tract Symptoms Using the UEDA Criteria.International neurourology journal · 2024Article
- Tension-free artisan tape: a low-cost option for cure of pelvic organ prolapse and stress incontinence.Annals of translational medicine · 2024Review
- A brief physiology and pathophysiology of the anorectum based on the Integral Theory paradigm.Annals of translational medicine · 2024Review
- Squatting-based exercises cure bedwetting in children and improve pain and bladder symptoms in premenopausal women.Annals of translational medicine · 2024Review
- Peripheral muscle force balance/imbalance in neurological binary control of bladder function and dysfunction.Annals of translational medicine · 2024Review
- Simulated operations (SOs) apply mechanical support to structures to confirm symptom causation.Annals of translational medicine · 2024Review
- A comparison of native vaginal and ligament surgery for cure of pelvic organ prolapse and overactive bladder.Annals of translational medicine · 2024Review
- Interstitial Cystitis: A Consequence of Weakened Uterosacral Ligaments Failing to Support Visceral Plexuses and Bladder Stretch Receptors, and Therefore Potentially Curable?International neurourology journal · 2022Article
- Defining urge as an uncontrolled micturition explains pathogenesis, informs cure and helps solve the burgeoning OAB crisis.Neurourology and urodynamics · 2022Review
- THE CASE AGAINST urethral failure is not a critical factor in female urinary incontinence. Now what? The integral theory system.Neurourology and urodynamics · 2022Article
- Late-occurring pain/other dysfunctions in midurethral sling class actions are likely caused by uterosacral ligament weakness, not implant or surgeon.Neurourology and urodynamics · 2022Review
- The emperor has no clothes: OAB can be cured surgically.International urogynecology journal · 2022Article
- An anatomical pathogenesis of lower urinary tract definitions from the 2002 ICS report symptoms, conditions, syndromes, urodynamics.Neurourology and urodynamics · 2022Review
- Efficacy of non-pharmacological interventions in patients with overactive bladder: A protocol for systematic review and network meta-analysis.Nursing open · 2022Article
- Non-Hunner's Interstitial Cystitis Is Different from Hunner's Interstitial Cystitis and May Be Curable by Uterosacral Ligament Repair.Urologia internationalis · 2022Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOveractive bladder (OAB) symptoms (urge, frequency, nocturia) are not generally considered surgically curable by learning institutions. The Integral Theory hypothesizes that OAB is a prematurely activated, but normal micturition reflex caused by loose suspensory ligaments and potentially curable surgically by repairing such ligaments. To test this hypothesis by surgical repair of loose cardinal and uterosacral ligaments in patients with 2 MATERIAL AND
methodsMulticenter prospective case control audit. 611 females, mean age 70. Inclusions: symptomatic apical prolapse of 2
results90% prolapse cure in 611 patients. Symptom incidence (% Cure at 12 months in brackets) was: urge incontinence: n = 310 (85%); frequency: n = 317 (83%); nocturia: n = 254 (68%); chronic pelvic pain (CPP): n = 194 (77%); fecal incontinence: n = 93 (65%). Statistics: McNemar x
conclusionsBladder & bowel incontinence and chronic pelvic pain occur in predictable groupings and are associated with apical prolapse. OAB symptom improvement with the TFS ligament repair provides a good alternative to anticholinergics, especially when considering their association with dementia causation. Application of the Integral Theory System has the potential to significantly improve clinical practice, QoL for ageing women, delaying entry into Nursing Homes and creating new scientific research directions. The take home message is that symptoms of chronic pelvic pain, bladder and bowel dysfunction occur in relatively predictable groups, caused by lax suspensory ligaments and can be cured or improved by TFS mini sling ligament repair.
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Registered trials
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