ReviewEFORT open reviews2016
Total knee arthroplasty and infection: how surgeons can reduce the risks.
Review in EFORT open reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Review
- The Economic Impact and Clinical Benefits of Intraosseous Injections in Total Knee Arthroplasty.Arthroplasty today · 2026Article
- The impact of "weekend effect" on the outcomes of total joint arthroplasty in the United States.International orthopaedics · 2025Article
- Periprosthetic Joint Infection Occurring Following a Femoral Subcutaneous Cyst: A Rare Complication Post-Total Knee Arthroplasty.Case reports in orthopedics · 2025Article
- Atypical Periprosthetic Joint Infection Post-Total Knee Arthroplasty: A Case of Actinomyces europaeus.Cureus · 2024Article
- Assessing the predictive value of pre- and post-operative inflammatory markers in patients undergoing total knee arthroplasty.Journal of orthopaedic surgery and research · 2024Article
- Evidence-based Approach for Prevention of Surgical Site Infection.Hip & pelvis · 2024Review
- A Water-Based Biocoating to Increase the Infection Resistance and Osteoconductivity of Titanium Surfaces.International journal of molecular sciences · 2024Article
- Article
- Validation of the antibacterial effect of topically applied tranexamic acid usingFrontiers in microbiology · 2024Article
- The Cost-Effectiveness of Normal-Saline Pulsed Lavage for Infection Prophylaxis in Total Joint Arthroplasty.Arthroplasty today · 2022Article
- Retrospective Study from a Single Center on the Efficacy of Pulsed Lavage Following Excision of Burns ≥30% of the Total Body Surface Area in 63 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Using the Phecode System to Identify the Preoperative Clinical Phenotypes Associated with Surgical Site Infection in Patients Undergoing Primary Total Knee Arthroplasty: The Sex Differences.Journal of clinical medicine · 2022Article
- Current Trends in Knee Arthroplasty: Are Italian Surgeons Doing What Is Expected?Medicina (Kaunas, Lithuania) · 2022Article
- Tranexamic Acid in Combination With Vancomycin or Gentamicin Has a Synergistic Effect Against Staphylococci.Frontiers in microbiology · 2022Article
- Late Acute Hematogenous Infections after Total Knee Arthroplasty: Results of Debridement, Antibiotics, and Implant Retention.The archives of bone and joint surgery · 2021Review
- The Impact of Femoral Nerve Anesthesia on Short-Term Clinical Outcomes and Opioid Claims After Total Knee Arthroplasty.Arthroplasty today · 2020Article
- Intestinal methicillin-resistantBone & joint research · 2020Article
- A potential risk factor of total knee arthroplasty: an infected Baker's cyst - a case report.BMC musculoskeletal disorders · 2020Article
- Skin avulsion injuries caused by the application of adhesive drapes during total knee arthroplasty: A case report.Medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Total joint arthroplasty (TJA) is one of the most common orthopaedic procedures. Nevertheless, several complications can lead to implant failure.Peri-prosthetic joint infections (PJI) certainly represent a significant challenge in TJA, constituting a major cause of prosthetic revision. The surgeon may have an important role in reducing the PJI rate by limiting the impact of significant risk factors associated to either the patient, the operative environment or the post-operative care.In the pre-operative period, several preventive measures may be adopted to manage reversible medical comorbidities. Other recognised pre-operative risk factors are urinary tract infections, intra-articular corticosteroid injections and nasal colonisation with Staphylococcus (S.) aureus, particularly the methicillin-resistant strain (MRSA).In the intra-operative setting, protective measures for PJI include antibiotic prophylaxis, surgical-site antisepsis and use of pre-admission chlorhexidine washing and pulsed lavage during surgery. In this setting, the use of plastic adhesive drapes and sterile stockinette, as well as using personal protection systems, do not clearly reduce the risk of infection. On the contrary, using sterile theatre light handles and splash basins as well as an increased traffic in the operating room are all associated with an increased risk for PJI.In the post-operative period, other infections causing transient bacteraemia, blood transfusion and poor wound care are considered as risk factors for PJI. Cite this article: Ratto N, Arrigoni C, Rosso F, Bruzzone M, Dettoni F, Bonasia DE, Rossi R. Total knee arthroplasty and infection: how surgeons can reduce the risks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.