ReviewEFORT open reviews2016
Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions.
Review in EFORT open reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- The Effects of Hyaluronic Acid on Gait Parameters in Patients with Knee Osteoarthritis: A Systematic Literature Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Efficacy and safety of quadriceps tendon autograft versus bone-patellar tendon-bone and hamstring tendon autografts for anterior cruciate ligament reconstruction: a systematic review and meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024Pooled it
- Intermittent vibrational stimulation can affect the lower limb kinematics three months after anterior cruciate ligament reconstruction: a randomised controlled trial.Scientific reports · 2025Trial
- Trial
- Inter-Session Repeatability of a Smartphone-Based Markerless System to Measure Segment Length and Lower-Limb Kinematics in Patients With End-Stage Knee Osteoarthritis.Orthopaedic surgery · 2026Article
- Radiographic Knee Osteoarthritis Identification Using Wearable Plantar Pressure: Secondary Cross-Sectional Analysis of Interpretable Framework Integrating Biomechanical Descriptors and the Multiscale Synergy Index.JMIR mHealth and uHealth · 2026Article
- Prevalence of Strength Deficits of Core and Hip Stabilizers in Knee Osteoarthritis: A Cross-Sectional Study.Musculoskeletal care · 2026Article
- Evaluation of the biomechanics of lower limbs in normal, overweight, and obese people using the SMART F-IMU system.Scientific reports · 2026Article
- Progression of bone and joint space deformity in patients with mild knee osteoarthritis: Data from the IMI-APPROACH cohort.Osteoarthritis and cartilage open · 2026Article
- Two-Dimensional Sagittal-Plane Gait Evaluation and Similarity Analysis in Parkinson's Disease Under ON and OFF Conditions: A Pilot Study.Brain sciences · 2026Article
- Shared Strides: Community-based, high-throughput biomechanics data collection in knee osteoarthritis.medRxiv : the preprint server for health sciences · 2026Article
- Bilateral knee-load limiting during uneven-terrain walking induces hip-dominant load redistribution in predictive gait simulations.Frontiers in medicine · 2026Article
- 3D-printed shoe soles with structural properties towards reducing knee adduction moments during walking.Frontiers in bioengineering and biotechnology · 2026Article
- Therapeutic Footwear for Medial Knee Osteoarthritis: Individualizing Midsole Stiffness Enhances Intended Kinetic Changes.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Functional data analysis of ground reaction forces combined with clinical measures for early knee osteoarthritis detection.Scientific reports · 2025Article
- Estimation of the External Knee Adduction Moment Using Inertial Measurement Unit Sensors on the Shank and Lower Back: A Pilot Study.Journal of functional morphology and kinesiology · 2025Article
- Three-Dimensional gait biomechanics in patients with mild knee osteoarthritis.Scientific reports · 2025Article
- Wearable Sensor Assessment of Gait Characteristics in Individuals Awaiting Total Knee Arthroplasty: A Cross-Sectional, Observational Study.Journal of functional morphology and kinesiology · 2025Article
- Unlocking Gait Analysis Beyond the Gait Lab: High-Fidelity Replication of Knee Kinematics Using Inertial Motion Units and a Convolutional Neural Network.Arthroplasty today · 2025Article
- The impact of PCA derived gait kinematic variations on estimated medial knee contact forces in a knee osteoarthritis population.Scientific reports · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Knee osteoarthritis (OA) is a painful and incapacitating disease affecting a large portion of the elderly population, for which no cure exists. There is a critical need to enhance our understanding of OA pathogenesis, as a means to improve therapeutic options.Knee OA is a complex disease influenced by many factors, including the loading environment. Analysing knee biomechanics during walking - the primary cyclic load-bearing activity - is therefore particularly relevant.There is evidence of meaningful differences in the knee adduction moment, flexion moment and flexion angle during walking between non-OA individuals and patients with medial knee OA. Furthermore, these kinetic and kinematic gait variables have been associated with OA progression.Gait analysis provides the critical information needed to understand the role of ambulatory biomechanics in OA development, and to design therapeutic interventions. Multidisciplinary research is necessary to relate the biomechanical alterations to the structural and biological components of OA. Cite this article: Favre J, Jolles BM. Analysis of gait, knee biomechanics and the physiopathology of knee osteoarthritis in the development of therapeutic interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.