Evidence map›Paper›PMID 28461825›Full record

ArticleKorean journal of pediatrics2017

Effect of tuberculosis treatment on leptin levels, weight gain, and percentage body fat in Indonesian children.

Maria Mexitalia, Yesi Oktavia Dewi, Adriyan Pramono, Mohammad Syarofil Anam

Open access · diamondAbstract read
In one paragraph

Article in Korean journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
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  6. Rifampicin efficacy against doxorubicin-induced cardiotoxicity in mice.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
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  8. Review
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  10. Changes in Host Response toFrontiers in cellular and infection microbiology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria MexitaliaDepartment of Pediatrics, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia.
Yesi Oktavia DewiDepartment of Pediatrics, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia.
Adriyan PramonoDepartment of Nutrition, Center of Nutrition Research (CENURE), Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
Mohammad Syarofil AnamDepartment of Pediatrics, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia.
Diponegoro University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTuberculosis (TB) remains a problem in the community. TB patients usually experience malnutrition, which is characterized by both decreased body weight (BW) and body fat percentage (BFP). Leptin, an important regulator of BW, also plays an important role in cellular immunity, which is integral to defense against

methodsThe design of this study was a group interrupted time series. The subjects were children with probable TB according to clinical criteria based on an Indonesian scoring system adopted from the Consensus of Expert Panel. BW; BFP; energy intake; fat and protein intake; and leptin levels before, 2 months after (intensive phase), and 6 months after (continuation phase) anti-TB treatment, were measured. About 40 children, aged 5-14 years, participated in this study.

resultsThe BW, BFP and leptin level increased from before treatment to after completion of the intensive phase and still showed an increased during the continuation phase: BW 18.65 kg, 19.75 kg, and 20.85 kg; BFP 18.3%, 19.5%, and 20.2%; and leptin level 1.9 mg/dL, 3.07 mg/dL, and 3.4 mg/dL, respectively (

conclusionLeptin level, BW, and BFP increased throughout the course of anti-TB treatment, compared with pretreatment values. Further research is needed to compare the results with data for healthy children.

Indexed as

ChildLeptinTuberculosis treatmentWeight gain

Identifiers

PMID28461825
PMCPMC5410618
OpenAlexW2608632085

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.