ArticleOncoTargets and therapy2017
Relationship between computed tomography morphology and prognosis of patients with stage I non-small cell lung cancer.
Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for the growth of ground-glass nodules in the lungs: A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- Unsupervised risk factor identification across cancer types and data modalities via explainable artificial intelligence.NPJ digital medicine · 2026Article
- A nomogram combining CT-based radiomic features with clinical features for the differentiation of benign and malignant cystic pulmonary nodules.Journal of cardiothoracic surgery · 2024Article
- [Clinical Multi-features Analysis of Cystic Lung Adenocarcinoma and Construction of Invasive Risk Prediction Model].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024Article
- Construction of a predictive model of 2-3 cm ground-glass nodules developing into invasive lung adenocarcinoma using high-resolution CT.Frontiers in medicine · 2024Article
- Growth characteristics of early-stage (IA) lung adenocarcinoma and its value in predicting lymph node metastasis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Clinicopathological and computed tomography features associated with recurrence-free survival of patients with small-sized peripheral invasive lung adenocarcinoma after sublobectomy.Quantitative imaging in medicine and surgery · 2023Article
- Correlations between iodine uptake, invasive CT features and pleural invasion in adenocarcinomas with pleural contact.Scientific reports · 2023Article
- The pattern of lymph node metastasis in peripheral pulmonary nodules patients and risk prediction models.Frontiers in surgery · 2022Article
- Discriminating Small-Sized (2 cm or Less), Noncalcified, Solitary Pulmonary Tuberculoma and Solid Lung Adenocarcinoma in Tuberculosis-Endemic Areas.Diagnostics (Basel, Switzerland) · 2021Article
- Intrapulmonic Cavity or Necrosis on Baseline CT Scan Serves as an Efficacy Predictor of Anti-PD-(L)1 Inhibitor in Advanced Lung Squamous Cell Carcinoma.Cancer management and research · 2021Article
- Prognostic value of morphological characteristics assessed by CT scan in patients with non-small cell lung cancer treated with nivolumab.Thoracic cancer · 2020Article
- Novel biologic factors correlated to visceral pleural invasion in early-stage non-small cell lung cancer less than 3 cm.Journal of thoracic disease · 2018Article
- Clinical and radiological characteristics of central pulmonary adenocarcinoma: a comparison with central squamous cell carcinoma and small cell lung cancer and the impact on treatment response.OncoTargets and therapy · 2018Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to explore the relationship between computed tomography morphology and prognosis of patients with stage I non-small cell lung cancer (NSCLC). From May 2009 to May 2011, a total of 124 patients diagnosed with stage I NSCLC were included. All patients had complete chest computed tomography scans. Five-year follow-up was conducted. Univariate and multivariate Cox regression analyses were performed to estimate the prognostic factors for patients with stage I NSCLC. The 5-year survival rate was 67.74% (84/124). The 5-year survival rates of patients with stage T1a, T1b, and T2a were 89.19%, 75.00%, and 41.86%, respectively. The 5-year survival rates of patients with homogeneity, inhomogeneity, vacuole, and cavity were 68.42%, 72.09%, 59.46%, and 83.33%, respectively. The 5-year survival rates of patients with different margin features were 83.33% (slick margin), 79.73% (lobulation sign), and 39.47% (short burr). The 5-year survival rates of patients with normal, halo, vessel convergence, bronchial transection, and vascular bundle thickening were 84.38%, 72.73%, 71.79%, 52.00%, and 47.06%, respectively. The 5-year survival rates of patients with normal and pleura thickening/indentation were 81.93% and 39.02%. Univariate analysis demonstrated that tumor node metastasis staging, tumor margin, tumor periphery, and pleural invasion were related to the prognosis of stage I NSCLC patients. Cox regression analysis confirmed that T2a stage, pleura thickening/indentation were independent risk factors for poor prognosis of stage I NSCLC. In conclusion, our findings indicate that T2a stage, pleura thickening/indentation might be prognostic factors in stage I NSCLC.
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