Evidence map›Paper›PMID 28461543›Full record

Trial reportAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2017

Predictive Associations of Music, Anxiety, and Sedative Exposure on Mechanical Ventilation Weaning Trials.

Breanna Hetland, Ruth Lindquist, Craig R Weinert, Cynthia Peden-McAlpine, Kay Savik, Linda Chlan

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03642002 (The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03642002 narecruitingnot on this mapstarted 2018, after this paper: background citation

The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2018 to 2028Enrolled178ConditionsAcute Respiratory Distress Syndrome, Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory FailureArmsToning, Ocean drum & SOK melody, SOK, Process, Holding Harmonic Container
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Effect of music therapy on outcomes of critically ill patients.World journal of critical care medicine · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Breanna HetlandBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota. bdh66@case.edu.
Ruth LindquistBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota.
Craig R WeinertBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota.
Cynthia Peden-McAlpineBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota.
Kay SavikBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota.
Linda ChlanBreanna Hetland is a postdoctoral fellow, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio. Ruth Lindquist is a professor, Cynthia Peden-McAlpine is an associate professor, and Kay Savik is senior statistician, School of Nursing, University of Minnesota, Minneapolis, Minnesota. Craig R. Weinert is an associate professor, School of Medicine, University of Minnesota. Linda Chlan is associate dean for nursing research, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic in Florida · US

Funding

Duke University Molecular Imaging CenterR24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2001 to 2006
$3.7M
Small Animal Imaging Resource ProgramU24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2007 to 2011
$2.2M
Symptom Management and Palliative Care Research in Adults with Advanced DiseaseT32NR014213 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI DALY, BARBARA · 2013 to 2017
$1.6M
Influence of Auditory Stimulation on Anxiety in Weaning from Mechanical VentilationF31NR014591 · NINR · UNIVERSITY OF MINNESOTA · PI HETLAND, BREANNA D · 2014 to 2015
$41k
NCI NIH HHS R24 CA092656NCI NIH HHS U24 CA092656NINR NIH HHS F31 NR014591NINR NIH HHS T32 NR014213
6 · The paper itself

Abstract

backgroundWeaning from mechanical ventilation requires increased respiratory effort, which can heighten anxiety and later prolong the need for mechanical ventilation.

objectivesTo examine the predictive associations of music intervention, anxiety, sedative exposure, and patients' characteristics on time to initiation and duration of weaning trials of patients receiving mechanical ventilation.

methodsA descriptive, correlational design was used for a secondary analysis of data from a randomized trial. Music listening was defined as self-initiated, patient-directed music via headphones. Anxiety was measured daily with a visual analog scale. Sedative exposure was operationalized as a daily sedation intensity score and a sedative dose frequency. Analyses consisted of descriptive statistics, graphing, survival analysis, Cox proportional hazards regression, and linear regression.

resultsOf 307 patients, 52% were women and 86% were white. Mean age was 59.3 (SD, 14.4) years, mean Acute Physiology and Chronic Health Evaluation III score was 62.9 (SD, 21.6), mean duration of ventilatory support was 8 (range, 1-52) days, and mean stay in the intensive care unit was 18 (range, 2-71) days. Music listening, anxiety levels, and sedative exposure did not influence time to initial weaning trial or duration of trials. Clinical factors of illness severity, days of weaning trials, and tracheostomy placement influenced weaning patterns in this sample.

conclusionsProspective studies of music intervention and other psychophysiological factors during weaning from mechanical ventilation are needed to better understand factors that promote successful weaning.

Indexed as

AnxietyCritical CareFemaleHumansHypnotics and SedativesMaleMiddle AgedMusicTime FactorsVentilator WeaningHypnotics and Sedatives

Identifiers

PMID28461543
PMCPMC5505274
OpenAlexW2610767868

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.