Evidence map›Paper›PMID 28461395›Full record

ArticleBlood2017

Eculizumab cessation in atypical hemolytic uremic syndrome.

Samuel A Merrill, Zachary D Brittingham, Xuan Yuan, Alison R Moliterno, C John Sperati, Robert A Brodsky

Abstract readLetter
In one paragraph

Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Diagnostic Performance of [Diagnostics (Basel, Switzerland) · 2026
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  12. Kidney international reports · 2024
    Article
  13. Monogenic Kidney Diseases in Kidney Transplantation.Kidney international reports · 2024
    Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Kidney diseases.Immunological reviews · 2023
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Samuel A MerrillDivision of Hematology and.
Zachary D BrittinghamDivision of Hematology and.
Xuan YuanDivision of Hematology and.
Alison R MoliternoDivision of Hematology and.
C John SperatiDivision of Nephrology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD.
Robert A BrodskyDivision of Hematology and.

Funding

TRAINING PROGRAM IN HEMATOLOGYT32HL007525 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ROBERT A BRODSKY · 1985 to 2026
$6.2M
Complementopathies: Genotype and PhenotypeR01HL133113 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BRODSKY, ROBERT A · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL133113NHLBI NIH HHS T32 HL007525
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Monoclonal, HumanizedAtypical Hemolytic Uremic SyndromeDrug Administration ScheduleDrug CostsFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRenal DialysisRetrospective StudiesAntibodies, Monoclonal, Humanizedeculizumab

Identifiers

PMID28461395
PMCPMC5520471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.