Evidence map›Paper›PMID 28460774›Full record

ReviewIndian heart journal

Nanomedicine in coronary artery disease.

Paurush Ambesh, Umberto Campia, Chukwudi Obiagwu, Rashika Bansal, Vijay Shetty, Gerald Hollander, Jacob Shani

Open access · goldAbstract readReview
In one paragraph

Review in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Paurush AmbeshDepartment of Internal Medicine, Maimonides Medical Center, New York City, USA. Electronic address: Paurush17@gmail.com.
Umberto CampiaDepartment of Cardiology, Brigham and Women's Hospital, Boston, USA.
Chukwudi ObiagwuDepartment of Cardiology, Maimonides Medical Center, New York City, USA.
Rashika BansalDepartment of Internal Medicine, St. Joseph Regional Medical Center, NJ, USA.
Vijay ShettyDepartment of Cardiology, Maimonides Medical Center, New York City, USA.
Gerald HollanderDepartment of Cardiology, Maimonides Medical Center, New York City, USA.
Jacob ShaniDepartment of Cardiology, Maimonides Medical Center, New York City, USA.
Maimonides Medical Center · USBrigham and Women's Hospital · USSt. Joseph Regional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomedicine is one of the most promising therapeutic modalities researchers are working on. It involves development of drugs and devices that work at the nanoscale (10-9m). Coronary artery disease (CAD) is responsible for more than a third of all deaths in age group >35 years. With such a huge burden of mortality, CAD is one of the diseases where nanomedicine is being employed for preventive and therapeutic interventions. Nanomedicine can effectively deliver focused drug payload at sites of local plaque formation. Non-invasive strategies include thwarting angiogenesis, intra-arterial thrombosis and local inflammation. Invasive strategies following percutaneous coronary intervention (PCI) include anti-restenosis and healing enhancement. However, before practical application becomes widespread, many challenges need to be dealt with. These include manufacturing at the nanoscale, direct nanomaterial cellular toxicity and visualization.

Indexed as

Coronary Artery DiseaseHumansNanomedicineTreatment OutcomeAtherosclerosisCoronary artery diseaseNanomedicineNanotechnology

Identifiers

PMID28460774
PMCPMC5414944
OpenAlexW2590228427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.