Observational studyIndian heart journal
Premature coronary artery disease in India: coronary artery disease in the young (CADY) registry.
Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk factors, lab parameters, angiographic characteristics and outcomes of coronary artery disease in young South Asian patients: a systematic review.The Journal of international medical research · 2023Pooled it
- Low quality cardiovascular care is important coronary risk factor in India.Indian heart journal · 2018Pooled it
- Article
- A Hybrid Chart Review of Premature Coronary Artery Disease: An Opportunity to Improve Diagnostic Excellence and Management.The Permanente journal · 2025Article
- Article
- Disentangling Dual Threats: Premature Coronary Artery Disease and Early-Onset Type 2 Diabetes Mellitus in South Asians.Journal of the Endocrine Society · 2023Review
- A comprehensive review of the components of nurse-coordinated care which are most effective in preventing coronary heart diseases.African health sciences · 2023Review
- Impact of premature coronary artery disease on adverse event risk followingFrontiers in cardiovascular medicine · 2023Article
- Article
- Association ofIndian journal of clinical biochemistry : IJCB · 2022Article
- Article
- Clinical profile & long-term natural history of symptomatic coronary artery disease in young patients (<30 yr).The Indian journal of medical research · 2020Article
- Premature Atherosclerotic Cardiovascular Disease: What Have We Learned Recently?Current atherosclerosis reports · 2020Review
- Article
- Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study.Wellcome open research · 2020Article
- Coronary artery disease in the young in the US population-based cohort.American journal of cardiovascular disease · 2020Article
- Can QRISK-3 and PREVENT Predict Premature Acute Coronary Syndrome in Adults under 40 Years? The Insights from Predicting the Risk of Acute Coronary Syndrome under 40 (PRACS-40) Study.Heart views : the official journal of the Gulf Heart AssociationArticle
- Secondary prevention of cardiovascular diseases in India: Findings from registries and large cohorts.Indian heart journalReview
- Observational
- ACPTI study: Being positive in a negative situation is not naivety - Trimetazidine still has role in symptomatic CAD patients.Indian heart journalArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronary artery disease (CAD) occurs at younger age in India but only a limited number of studies have evaluated risk factors and management status. This is a multisite observational registry to assess risk factors and treatment patterns in young patients presenting with acute coronary syndrome (ACS) and stable ischemic heart disease (IHD).
methodsWe recruited 997 young patients (men <55, women <65y) presenting with ACS or stable IHD successively at 22 centers across India. Details of baseline risk factors and management status were obtained. Descriptive statistics are reported.
resultsMean age of participants was 49.1±8y, 72% were men and 68% had ACS. Family history of CAD was in 50%, diabetes 44%, hypertension 49%, history of dyslipidemia 11%, smoking/tobacco use 39%, and sedentary habits in 20%. 1.3% had "possible familial hypercholesterolemia". Metabolic risk factors (high BMI, diabetes and hypertension) were significantly greater in women (p<0.01). Women were older at diagnosis of CAD and presented more often with non-ST elevation ACS. In the study cohort antiplatelet use was in 85%, beta-blockers 38%, statins 63% and ACE inhibitors/ARBs in 41% while in ACS patients it was 80.5%, 54.6%, 80.8% and 40.8%, respectively. 35.9% patients underwent percutaneous coronary intervention while coronary bypass surgery was performed in 10.4%.
conclusionsConventional risk factors including family history continue to play a pivotal role in premature CAD in Indians. Women have more of metabolic risk factors, present at a later age and have non-ST elevation ACS more often. There is a need to focus on improving use of evidence-based drug therapies and interventions.
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