Evidence map›Paper›PMID 28460758›Full record

ArticleIndian heart journal

Subclinical ventricular repolarization abnormality in uncontrolled compared with controlled treated hypertension.

Marwan S M Al-Nimer, Ismail I Hussein

Abstract readComparative Study
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marwan S M Al-NimerDepartment of Pharmacology, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq. Electronic address: alnimermarwan@ymail.com.
Ismail I HusseinDepartment of Physiology, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntihypertensive medications have variable effects on the duration of the QT interval. This study aims to demonstrate the subclinical ventricular conduction defect in treating hypertensive patients taking in consideration the status of the blood pressure control with the antihypertensive agents.

methodsThis cross-section study was performed at the Departments of Physiology and Pharmacology, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq. A total number of 97 hypertensive patients (30 males and 67 females) were eligible to enroll in the study. The patients were grouped into controlled hypertension (Group I) and uncontrolled hypertension (Group II). Each participant is subjected to the electrocardiograph (ECG) investigation. A QT nomogram plot used to identify the patients who are vulnerable or at risk of developing cardiac arrhythmias.

resultsThere were no significant differences in the values of the electrocardiogram determinants between Group I and Group II. Abnormal prolonged QTcB interval observed in 18 out of 80 (22.5%) patients of Group II compared with 4 out of 17. The JT index value of ≥112 was observed in 20 out of 80 (25%) patients of Group II compared with 6 out of 17 (35.3%) patients of Group I. A significant correlation between the QTcB duration with JT index observed in both Groups I and II.

conclusionPatients with hypertension have variability in ventricular repolarization (QTcB and JT) irrespective of their blood pressure control putting them at higher risk of cardiac arrhythmias.

Indexed as

ElectrocardiographyAgedAntihypertensive AgentsArrhythmias, CardiacCross-Sectional StudiesFemaleFollow-Up StudiesHeart Conduction SystemHeart RateHeart VentriclesHumansHypertensionMaleMiddle AgedRetrospective StudiesAntihypertensive AgentsAntihypertensive agentsHypertensionJTc intervalQTc intervalQT nomogram

Identifiers

PMID28460758
PMCPMC5414943

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