ArticleNanoscale research letters2017
Electrospun Poly(ε-caprolactone) Composite Nanofibers with Controlled Release of Cis-Diamminediiodoplatinum for a Higher Anticancer Activity.
Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- Electrospun Polycaprolactone Nanofibers: Current Research and Applications in Biomedical Application.Advanced pharmaceutical bulletin · 2022Review
- Synergistic effects of silver nanoparticles and cisplatin in combating inflammation and hyperplasia of airway stents.Bioactive materials · 2022Article
- Preparation of PCL Electrospun Fibers Loaded with Cisplatin and Their Potential Application for the Treatment of Prostate Cancer.Emergency medicine international · 2022Review
- Biotechnological Applications of Polymeric Nanofiber Platforms Loaded with Diverse Bioactive Materials.Polymers · 2021Review
- Polymer-Based Electrospun Nanofibers for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poly(ε-caprolactone) (PCL) nanofibers were prepared by electrospun, on which the cis-diamminediiodoplatinum (cis-DIDP) was loaded, cis-DIDP@PCL, which effectively overcame cis-DIDP from dissociation or premature interaction with other bimolecular groups. Meanwhile, the toxicity and cross-resistance of cis-DIDP were reduced greatly. In vitro, cis-DIDP released from the PCL nanofibers eradicated the tumor cells around twice times more than free cis-DIDP, even better than cisplatin. Furthermore, cis-DIDP@PCL could controllably release cis-DIDP in different sustained-release solution based on our experiment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.