ArticleOncotarget2017
Ultrasonographic characteristics of medullary thyroid carcinoma: a comparison with papillary thyroid carcinoma.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- A Rare Collision Medullary and Papillary Thyroid Carcinoma in Autoimmune Thyroid Disease: Case Report.Oncology research · 2026Article
- Using Elastographic Stiffness to Improve Risk Stratification in Medullary Thyroid Carcinoma.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Diagnostic Accuracy of Fine Needle Aspiration Cytology for Thyroid Tumours at a Tertiary Hospital in Northern Tanzania.The East African health research journal · 2025Article
- Molecular imaging and related therapeutic options for medullary thyroid carcinoma: state of the art and future opportunities.Reviews in endocrine & metabolic disorders · 2024Review
- Concurrent Medullary Carcinoma and Hashimoto's Thyroiditis: A Case Report with an Emphasis on US Features.Journal of the Korean Society of Radiology · 2023Article
- Ultrasound characteristics of follicular and parafollicular thyroid neoplasms: diagnostic performance of artificial neural network.Thyroid research · 2023Article
- Using preoperative ultrasound vascularity characteristics to estimate medullary thyroid cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Evaluation of PD-L1 antigen expression using immunohistochemistry technique in medullary thyroid carcinoma samples.International journal of physiology, pathophysiology and pharmacology · 2023Article
- Management of Thyroid Nodules.Sisli Etfal Hastanesi tip bulteni · 2023Review
- Diagnostic efficiency of existing guidelines and the AI-SONIC™ artificial intelligence for ultrasound-based risk assessment of thyroid nodules.Frontiers in endocrinology · 2023Article
- Capsular extension at ultrasound is associated with lateral lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study.BMC cancer · 2021Article
- Diagnostic Utility of Radiomics in Thyroid and Head and Neck Cancers.Frontiers in oncology · 2021Review
- Medullary thyroid carcinoma: recent advances in identification, treatment, and prognosis.Therapeutic advances in endocrinology and metabolism · 2021Review
- Molecular Aspects of Thyroid Calcification.International journal of molecular sciences · 2020Review
- Long-term ultrasound follow-up of intrathyroidal ectopic thymus in children.Journal of endocrinological investigation · 2020Article
- Clinical and ultrasonographic features of medullary thyroid microcarcinomas compared with papillary thyroid microcarcinomas: a retrospective analysis.BMC medical imaging · 2020Article
- Article
- Medullary thyroid carcinoma combined with papillary thyroid carcinoma: case report and literature review.International journal of clinical and experimental pathology · 2020Article
- Diagnosis and pathologic characteristics of medullary thyroid carcinoma-review of current guidelines.Current oncology (Toronto, Ont.) · 2019Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was designed to explore differences in the ultrasonographic characteristics of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC). This study included 35 cases of MTC and 96 cases of PTC that were surgically and pathologically confirmed. Preoperative ultrasound images were retrospectively reviewed by two physicians (with 5 years' experience in thyroid ultrasound) under the premise of unknown pathological results. Various ultrasonic features of nodules were assessed objectively. The clinical features of components were determined by other physicians. Age, sex, unilateral or bilateral involvement of thyroid gland, lesion size, margin, shape, echogenicity, calcification, intranodular blood flow, cervical lymph node, and tumor node metastasis (TNM) stage were compared between MTC and PTC groups. Age, sex, involvement of the thyroid gland, margin, and calcification were similar for the MTC and PTC groups. Compared with the PTC group, the lesion size in the MTC group was significantly larger (P < 0.001). A taller-than-wide shape (aspect ratio > 1) was significantly less likely in the MTC group than the PTC group (P < 0.001). A mixed echogenicity was significantly more common in the MTC group than the PTC group (P = 0.003). The MTC group had significantly enhanced intranodular blood flow (P < 0.001). The TNM stage of the MTC group was significantly higher than that of PTC group (P = 0.001). Medullary thyroid carcinomas differ significantly from PTCs in lesion size, shape, echogenicity, and intranodular blood flow.
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