Trial reportAddictive behaviors2017
Integrated, exposure-based treatment for PTSD and comorbid substance use disorders: Predictors of treatment dropout.
Trial report in Addictive behaviors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01338506 (Integrated Treatment of Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Post-traumatic Stress Disorder and Substance Use Disorders), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Integrated Treatment of Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Post-traumatic Stress Disorder and Substance Use Disorders
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cognitive Behavioural Therapy and Dual Diagnosis: A Systematic Review Exploring Its Effectiveness and Implications for Nursing Practice.International journal of mental health nursing · 2025Pooled it
- Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.International journal of methods in psychiatric research · 2025Pooled it
- A systematic review and meta-analysis of psychological interventions for comorbid post-traumatic stress disorder and substance use disorder.European journal of psychotraumatology · 2022Pooled it
- Substance use predictors of attendance among veterans in integrated PTSD and alcohol use disorder treatment.Journal of substance abuse treatment · 2021Trial
- Concurrent treatment of substance use disorders and PTSD using prolonged exposure: A randomized clinical trial in military veterans.Addictive behaviors · 2019Trial
- Substance use disorders and PTSD: Examining substance use, PTSD symptoms, and dropout following imaginal exposure.Addictive behaviors · 2019Trial
- Narrative exposure therapy for post-traumatic stress symptoms in women who are incarcerated: an open pilot study.European journal of psychotraumatology · 2026Article
- The role of distress tolerance in treatment of posttraumatic stress and substance use disorders: a systematic review.Cognitive behaviour therapy · 2026Review
- Discontinuation of mental health treatment among Canadian military personnel.Journal of military, veteran and family health · 2024Article
- A compassion microintervention targeting stress reactivity among sexual minority women and transgender/nonbinary people: Study protocol for a randomized controlled trial.Contemporary clinical trials · 2024Article
- Alcohol-Related Problems As Moderators of PTSD Symptom Change During Use of a Web-Based Intervention for Hazardous Drinking and PTSD.Journal of studies on alcohol and drugs · 2024Article
- Impulsivity, trauma history, and interoceptive awareness contribute to completion of a criminal diversion substance use treatment program for women.Frontiers in psychology · 2024Article
- Seeing the forest for the trees: Predicting attendance in trials for co-occurring PTSD and substance use disorders with a machine learning approach.Journal of consulting and clinical psychology · 2021Article
- Expanded Roles and Recommendations for Stakeholders to Successfully Reintegrate Modern Warriors and Mitigate Suicide Risk.Frontiers in psychology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
High rates of comorbid posttraumatic stress disorder (PTSD) and substance use disorders (SUD) have been noted in veteran populations. Fortunately, there are a number of evidence-based psychotherapies designed to address comorbid PTSD and SUD. However, treatments targeting PTSD and SUD simultaneously often report high dropout rates. To date, only one study has examined predictors of dropout from PTSD/SUD treatment. To address this gap in the literature, this study aimed to 1) examine when in the course of treatment dropout occurred, and 2) identify predictors of dropout from a concurrent treatment for PTSD and SUD. Participants were 51 male and female veterans diagnosed with current PTSD and SUD. All participants completed at least one session of a cognitive-behavioral treatment (COPE) designed to simultaneously address PTSD and SUD symptoms. Of the 51 participants, 22 (43.1%) dropped out of treatment prior to completing the full 12 session COPE protocol. Results indicated that the majority of dropout (55%) occurred after session 6, with the largest amount of dropout occurring between sessions 9 and 10. Results also indicated a marginally significant relationship between greater baseline PTSD symptom severity and premature dropout. These findings highlight inconsistencies related to timing and predictors of dropout, as well as the dearth of information noted about treatment dropout within PTSD and SUD literature. Suggestions for procedural changes, such as implementing continual symptom assessments during treatment and increasing dialog between provider and patient about dropout were made with the hopes of increasing consistency of findings and eventually reducing treatment dropout.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.