Evidence map›Paper›PMID 28460173›Full record

ArticleACS chemical neuroscience2017

A Visible-Light-Sensitive Caged Serotonin.

Ricardo Cabrera, Oscar Filevich, Beatriz García-Acosta, Jegath Athilingam, Kevin J Bender, Kira E Poskanzer, Roberto Etchenique

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. RuBi-Ruxolitinib: A Photoreleasable Antitumor JAK Inhibitor.Journal of the American Chemical Society · 2024
    Article
  6. Ruthenium-Based Photoactivated Chemotherapy.Journal of the American Chemical Society · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Photoswitchable Serotonins for Optical Control of the 5-HTAngewandte Chemie (International ed. in English) · 2022
    Article
  11. Article
  12. Article
  13. New Designs for Phototherapeutic Transition Metal Complexes.Angewandte Chemie (International ed. in English) · 2020
    Review
  14. Review
  15. Probing Single SynapsesFrontiers in synaptic neuroscience · 2019
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ricardo CabreraDepartamento de Química Inorgánica, Analítica y Química Física, INQUIMAE, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, CONICET, Ciudad Universitaria Pabellón 2, AR1428EHA Buenos Aires, Argentina.
Oscar FilevichLaboratorio de Neurobiología Molecular, BIOMED, Pontificia Universidad Católica Argentina, CONICET, C1107AFB Buenos Aires, Argentina.
Beatriz García-AcostaDepartamento de Química Inorgánica, Analítica y Química Física, INQUIMAE, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, CONICET, Ciudad Universitaria Pabellón 2, AR1428EHA Buenos Aires, Argentina.
Jegath AthilingamKavli Institute for Fundamental Neuroscience, UCSF Weill Institute for Neuroscience , San Francisco, California, United States.
Kevin J BenderKavli Institute for Fundamental Neuroscience, UCSF Weill Institute for Neuroscience , San Francisco, California, United States.
Kira E PoskanzerKavli Institute for Fundamental Neuroscience, UCSF Weill Institute for Neuroscience , San Francisco, California, United States.
Roberto EtcheniqueDepartamento de Química Inorgánica, Analítica y Química Física, INQUIMAE, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, CONICET, Ciudad Universitaria Pabellón 2, AR1428EHA Buenos Aires, Argentina.ORCID 0000-0002-5485-8710
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of California, San Francisco · US

Funding

A Functional Taxonomy of Cortical AstrocytesR01NS099254 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Evan Harriman Feinberg · 2017 to 2026
$4.1M
Cellular mechanisms for dopaminergic control of learning in prefrontal cortexR01DA035913 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BENDER, KEVIN J · 2013 to 2017
$1.7M
Serotonergic Modulation of Fast-Spiking Interneurons in Medial Prefrontal CortexF31MH111219 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ATHILINGAM, JEGATH · 2016 to 2017
$65k
NIDA NIH HHS R01 DA035913NIMH NIH HHS F31 MH111219NINDS NIH HHS R01 NS099254
6 · The paper itself

Abstract

Serotonin, or 5-hydroxytryptamine (5HT), is an important neurotransmitter in the nervous system of both vertebrates and invertebrates. Deficits in 5HT signaling are responsible for many disabling psychiatric conditions, and its molecular machinery is the target of many pharmaceuticals. We present a new 5HT phototrigger, the compound [Ru(bpy)

Indexed as

LightAnimalsMiceNeuronsPrefrontal CortexRutheniumSerotoninRutheniumSerotoninneurophysiologyphototriggersRuthenium complexserotonin

Identifiers

PMID28460173
PMCPMC5573591
OpenAlexW2610875386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.