Evidence map›Paper›PMID 28460153›Full record

ArticleJournal of medical virology2017

Cytokine/chemokine expression associated with Human Pegivirus (HPgV) infection in women with HIV.

Jason T Blackard, Gang Ma, Jeffrey A Welge, Lynn E Taylor, Kenneth H Mayer, Robert S Klein, David D Celentano, Jack D Sobel, Denise J Jamieson, Caroline C King

Abstract read
In one paragraph

Article in Journal of medical virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Molecular characterization and frequency of human pegivirus type 1 (HPgV-1) in kidney transplant recipients from Central-West Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Jason T BlackardDivision of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID 0000-0003-2876-3811
Gang MaDivision of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Jeffrey A WelgeDepartments of Psychiatry and Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Lynn E TaylorMiriam Hospital and Department of Medicine, Brown University, Providence, Rhode Island.
Kenneth H MayerBeth Israel Deaconess Medical Center and the Fenway Institute, Boston, Massachusetts.
Robert S KleinHudson Infectious Diseases Associates, Briarcliff Manor, New York.
David D CelentanoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Jack D SobelDivision of Infectious Diseases, School of Medicine, Wayne State University, Detroit, Michigan.
Denise J JamiesonDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Caroline C KingDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
University of Cincinnati Medical Center · USCenters for Disease Control and Prevention · USAcademy of Management · USBeth Israel Deaconess Medical Center · USBrown University · USJohns Hopkins University · USWayne State University · US

Funding

Clinical Relevance of GB Virus C & Hepatitis C Virus in HIV+ WomenR21AI081564 · NIAID · UNIVERSITY OF CINCINNATI · PI BLACKARD, JASON T · 2009 to 2010
$430k
NIAID NIH HHS R21 AI081564
6 · The paper itself

Abstract

A beneficial impact of the Human Pegivirus (HPgV)-formerly called GB virus C (GBV-C)-on HIV disease progression has been reported previously. One possible mechanism by which HPgV inhibits HIV replication is an alteration of the cytokine/chemokine milieu. Their expression has not been specifically evaluated in women despite their influence on disease progression and the possibility of gender-based differences in expression. Moreover, the impact of HPgV genotype on cytokine/chemokine expression is unknown. Sera levels of IL-2, IL-4, IL-7, IL-8, IL-10, IL-12p70, IL-13, IFNγ, TNFα, IP-10, MIP-1α, MIP-1β, and TGF-β

Indexed as

AdultChemokinesCytokinesDisease ProgressionFemaleFlaviviridae InfectionsGB virus CGenotypeHIV InfectionsHumansInterleukin-12Interleukin-2Interleukin-4Middle AgedProspective StudiesRNA, ViralChemokinesCytokinesInterleukin-12Interleukin-2Interleukin-4RNA, ViralTransforming Growth Factor beta1chemokinecytokineGB virus C (GBV-C)HIVhuman pegivirus (HPgV)women

Identifiers

PMID28460153
PMCPMC5603382
OpenAlexW2611071535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.