Evidence map›Paper›PMID 28460092›Full record

ArticleGenome biology and evolution2017

Comparative Genomics of Host-Symbiont and Free-Living Oceanobacillus Species.

Anupam Kumar Mondal, Jitendra Kumar, Rajesh Pandey, Shashank Gupta, Manoj Kumar, Gourja Bansal, Mitali Mukerji, Debasis Dash, Nar Singh Chauhan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Genome biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Role of Gut Microbiome in Autism Spectrum Disorder and Its Therapeutic Regulation.Frontiers in cellular and infection microbiology · 2022
    Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anupam Kumar MondalG.N.Ramachandran Knowledge Centre for Genome Informatics, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Jitendra KumarDepartment of Biochemistry, Maharshi Dayanand University, Rohtak, Haryana, India.
Rajesh PandeyCSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Shashank GuptaCSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Manoj KumarDepartment of Biochemistry, Maharshi Dayanand University, Rohtak, Haryana, India.
Gourja BansalG.N.Ramachandran Knowledge Centre for Genome Informatics, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Mitali MukerjiAcademy of Scientific & Innovative Research, New Delhi, India.
Debasis DashG.N.Ramachandran Knowledge Centre for Genome Informatics, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Nar Singh ChauhanDepartment of Biochemistry, Maharshi Dayanand University, Rohtak, Haryana, India.
Institute of Genomics and Integrative Biology · INMaharshi Dayanand University · INAcademy of Scientific and Innovative Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survival in a given environment requires specific functions, so genomic variation is anticipated within in individual taxonomic groups that exhibit a large diversity in lifestyles. In this study, we sequence and assemble the genome of Oceanobacillus faecalis strain HM6, a resident of the human gut. Using the genus Oceanobacillus and the HM6 draft genome sequence, we explore the functional requirements for survival in a symbiotic arrangement within the human gut, in contrast to free living in the environment. Comparative genomics of seven available Oceanobacillus complete genomes highlight a genomically heterogeneous group. Our analysis did not find strict phylogenetic separation between free-living and host-symbiont Oceanobacillus members. By comparing functional gene content between host-associated and free-living species, we identified candidate genes that are potentially involved in symbiotic lifestyles, including phosphotransferase genes, transporters and two component response regulators. This study summarizes genomic and phylogenetic differences in the Oceanobacillus genus. Additionally, we highlight functions that may be key for survival in the human gut community.

Indexed as

BacillaceaeEcosystemGastrointestinal MicrobiomeGenome, BacterialHumansPhylogenySequence Analysis, DNASymbiosiscomparative genomicsgut microbiomehost–microbe symbiosisOceanobacillus

Identifiers

PMID28460092
PMCPMC5425236
OpenAlexW2607760426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.