Evidence map›Paper›PMID 28458918›Full record

ArticleVirus evolution2017

Transmission fitness of drug-resistant HIV revealed in a surveillance system transmission network.

Joel O Wertheim, Alexandra M Oster, Jeffrey A Johnson, William M Switzer, Neeraja Saduvala, Angela L Hernandez, H Irene Hall, Walid Heneine

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Transmitted Drug Resistance Among Human Immunodeficiency Virus (HIV)-1 Diagnoses in the United States, 2014-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  16. Article
  17. Review
  18. Pretreatment and Acquired Antiretroviral Drug Resistance Among Persons Living With HIV in Four African Countries.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joel O WertheimDepartment of Medicine, University of California, San Diego, CA, 92093, USA.
Alexandra M OsterDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
Jeffrey A JohnsonDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
William M SwitzerDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
Neeraja SaduvalaICF International, Atlanta, GA, 30329, USA.
Angela L HernandezDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
H Irene HallDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
Walid HeneineDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA.
Centers for Disease Control and Prevention · USICF International (United States) · US

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN JANET LITTLE · 1994 to 2026
$78.4M
Public Health Implications of HIV Transmission NetworksK01AI110181 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERTHEIM, JOEL OKRENT · 2014 to 2018
$668k
NIAID NIH HHS K01 AI110181NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

Test-and-treat programs are central to the global control of HIV, but transmitted drug resistance threatens the effectiveness of these programs. HIV mutations conferring resistance to antiretroviral drugs reduce replicative fitness

Indexed as

drug resistancefitnessHIVtransmission network

Identifiers

PMID28458918
PMCPMC5399924
OpenAlexW2606988923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.