ArticleEuropean journal of translational myology2017
Denervation does not Induce Muscle Atrophy Through Oxidative Stress.
Article in European journal of translational myology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 36 citations in OpenAlex.
- Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression.Free radical biology & medicine · 2026Article
- Oleanolic acid alleviates obesity-induced skeletal muscle atrophy via the PI3K/Akt signaling pathway.FEBS open bio · 2024Article
- Early Changes in Porcine Larynges Following Injection of Motor-Endplate Expressing Muscle Cells for the Treatment of Unilateral Vocal Fold Paralysis.The Laryngoscope · 2024Article
- Sarcopenia Is Associated with Changes in Circulating Markers of Antioxidant/Oxidant Balance and Innate Immune Response.Antioxidants (Basel, Switzerland) · 2023Article
- Targeting Mitochondria and Oxidative Stress in Cancer- and Chemotherapy-Induced Muscle Wasting.Antioxidants & redox signaling · 2023Review
- Functional Nutrients to Ameliorate Neurogenic Muscle Atrophy.Metabolites · 2022Review
- Transcranial Magnetic Stimulation Improves Muscle Involvement in Experimental Autoimmune Encephalomyelitis.International journal of molecular sciences · 2021Article
- Effects of photobiomodulation therapy on functional recovery, angiogenesis and redox status in denervated muscle of rats.Einstein (Sao Paulo, Brazil) · 2021Article
- 2019Spring PaduaMuscleDays: Translational Myology and Mobility Medicine.European journal of translational myology · 2019Article
- HMGB1/autophagy pathway mediates the atrophic effect of TGF-β1 in denervated skeletal muscle.Cell communication and signaling : CCS · 2018Article
- Report on Abstracts of the 15th Meeting of IIM, the Interuniversity Institute of Myology - Assisi (Italy), October 11-14, 2018.European journal of translational myology · 2018Article
- Do neurogenic and cancer-induced muscle atrophy follow common or divergent paths?European journal of translational myology · 2018Article
- Muscle spindles of the rat sternomastoid muscle.European journal of translational myology · 2018Article
- Increasing autophagy does not affect neurogenic muscle atrophy.European journal of translational myology · 2018Article
- EJTM3 is also covering Mobility and Medicine at large, an update.European journal of translational myology · 2018Article
- Chemotherapy-induced muscle wasting: an update.European journal of translational myology · 2018Article
- Culture conditions influence satellite cell activation and survival of single myofibers.European journal of translational myology · 2018Article
- HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses.Skeletal muscle · 2018Article
- Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial - Chapter I - Foreword.European journal of translational myology · 2018Article
- From Ejtm (European Journal of Translational Myology) to Ejt3M (European Journal of Translational Myology, Mobility, Medicine).European journal of translational myology · 2018Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness. Furthermore, denervation induces oxidative stress in skeletal muscle, which is thought to contribute to the induction of skeletal muscle atrophy. Several muscle diseases are characterized by denervation, but the molecular pathways contributing to muscle atrophy have been only partially described. Our study delineates the kinetics of activation of oxidative stress response in skeletal muscle following denervation. Despite the denervation-dependent induction of oxidative stress in skeletal muscle, treatments with anti-oxidant drugs do not prevent the reduction of muscle mass. Our results indicate that, although oxidative stress may contribute to the activation of the response to denervation, it is not responsible by itself of oxidative damage or neurogenic muscle atrophy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.