Evidence map›Paper›PMID 28458735›Full record

ReviewThe open virology journal2017

Features of Maternal HIV-1 Associated with Lack of Vertical Transmission.

Nafees Ahmad, Aamir N Ahmad, Shahid N Ahmad

Open access · diamondAbstract readReview
In one paragraph

Review in The open virology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nafees AhmadDepartment of Immunobiology, College of Medicine, The University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA.
Aamir N AhmadDepartment of Immunobiology, College of Medicine, The University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA.
Shahid N AhmadDepartment of Immunobiology, College of Medicine, The University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA.
University of Arizona · US

Funding

Molecular Mechanisms of HIV-1 Pathogenesis in InfantsR21AI040378 · NIAID · UNIVERSITY OF ARIZONA · PI AHMAD, NAFEES · 2002 to 2002
$265k
EVALUATION OF THE HIV-1 SUBTYPE C ISOLATES FROM INDIAR03TW001345 · FIC · UNIVERSITY OF ARIZONA · PI AHMAD, NAFEES · 2000 to 2002
$110k
FIC NIH HHS R03 TW001345NIAID NIH HHS R21 AI040378
6 · The paper itself

Abstract

HIV-1 is transmitted from mother-to-child (vertical transmission) at an estimated rate of approximately 30% without any antiretroviral therapy (ART). However, administration of ART during pregnancy considerably diminishes the rate of mother-to-child transmission of HIV-1, which has become a standard of perinatal care in HIV-infected pregnant females in developed countries. Moreover, a majority of children born to HIV-infected mothers are uninfected without any ART. In addition, characteristics of HIV-1 and/or cellular factors in the mothers may play a role in influencing or preventing vertical transmission. Several studies, including from our laboratory have characterized the properties of HIV-1 from infected mothers that transmitted HIV-1 to their infants (transmitting mothers) and compared with those mothers that failed to transmit HIV-1 to their infants (non-transmitting mothers) in the absence of ART. One of the striking differences observed was that the non-transmitting mothers harbored a less heterogeneous HIV-1 population than transmitting mothers in the analyzed HIV-1 regions of p17

Indexed as

HIV-1HIV-1 accessory genesHIV-1 structural genesMaternal HV-1Vertical transmission

Identifiers

PMID28458735
PMCPMC5388788
OpenAlexW2597017377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.