ArticleInternational journal of chronic obstructive pulmonary disease2017
Frailty syndrome in ambulatory patients with COPD.
Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 5 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Frailty and its influence on mortality and morbidity in COPD: A Systematic Review and Meta-Analysis.Internal and emergency medicine · 2023Pooled it
- Prevalence and risk factors of frailty in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis.European geriatric medicine · 2023Pooled it
- Systematic review and meta-analysis of prevalence, trajectories, and clinical outcomes for frailty in COPD.NPJ primary care respiratory medicine · 2023Pooled it
- Prevalence of sarcopenia in patients with COPD through different musculature measurements: An updated meta-analysis and meta-regression.Frontiers in nutrition · 2023Pooled it
- Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Frailty and COPD: a bidirectional relationship in the context of systemic and accelerated ageing.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Development and validation of a clinical nomogram for frailty prediction in older COPD patients: a machine learning approach.BMC geriatrics · 2026Article
- Advances in pathophysiology and assessment methods of chronic obstructive pulmonary disease with frailty.Chinese medical journal pulmonary and critical care medicine · 2025Review
- Impact of Frailty on Activities of Daily Living and Length of Hospitalization in Acute Exacerbations of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025Article
- Lower bioelectrical impedance phase angle is associated with COPD and is a marker for increased risks in elderly COPD patients.Frontiers in medicine · 2025Article
- Developing and validating machine learning-based prediction models for frailty occurrence in those with chronic obstructive pulmonary disease.Journal of thoracic disease · 2024Article
- Unveiling the Knowledge Frontier: A Scientometric Analysis of COPD with Sarcopenia.International journal of chronic obstructive pulmonary disease · 2024Article
- Multidimensional Frailty Instruments Can Predict Acute Exacerbations Within One Year in Patients with Stable Chronic Obstructive Pulmonary Disease: A Retrospective Longitudinal Study.International journal of chronic obstructive pulmonary disease · 2024Article
- Analyses of Factors Associated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Review.International journal of chronic obstructive pulmonary disease · 2023Review
- The Timed Up and Go test predicts frailty in patients with COPD.NPJ primary care respiratory medicine · 2022Article
- Daily living activities, exercise capacity, cognition, and balance in COPD patients with and without frailty.Irish journal of medical science · 2022Article
- Frailty Syndrome-Fall Risk and Rehabilitation Management Aided by Virtual Reality (VR) Technology Solutions: A Narrative Review of the Current Literature.International journal of environmental research and public health · 2022Review
- Four different frailty models predict health outcomes in older patients with stable chronic obstructive pulmonary disease.BMC geriatrics · 2022Article
- Frailty in Lung Transplantation: Candidate Assessment and Optimization.Transplantation · 2021Article
- Frailty increases the risk for developing urinary tract infection among 79,887 patients with diabetic mellitus and chronic kidney disease.BMC geriatrics · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were to determine the prevalence of frailty in COPD patients and to identify the associated factors in these populations. A cross-sectional study of COPD patients who attended a COPD clinic was conducted from May 2015 to December 2016. Baseline characteristics were collected, and the diagnosis of frailty was based on the FRAIL (fatigue, resistance, ambulation, illnesses, and loss of weight) scale. Descriptive statistics were used to analyze baseline data. Factors associated with frailty were analyzed using univariate and multivariate regression analyses. The results showed that the prevalence rates of frailty and pre-frailty were 6.6% (eight out of 121 cases) and 41.3% (50 out of 121 cases), respectively, among COPD patients. Fatigue was the most common component of the FRAIL scale that was found more frequently in frail patients than in non-frail patients (odds ratio [OR] 91.9). Factors associated with frailty according to multivariate analyses were comorbid cancer (adjusted OR [AOR] 45.8), at least two instances of nonelective admission over the past 12 months (AOR 112.5), high waist circumference (WC) (AOR 1.3), and presence of sarcopenia (AOR 29.5). In conclusion, frailty affected 6.6% of stable COPD patients. Cancer, two or more instances of nonelective hospitalization over the past 12 months, high WC, and presence of sarcopenia were associated with frailty. Early identification and intervention in high-risk patients is recommended to prevent or delay the adverse outcomes of frailty.
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