Evidence map›Paper›PMID 28458518›Full record

ArticleDrug design, development and therapy2017

Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity through the alleviation of mitochondrial dysfunction.

Ai-Ling Cui, Ying-Hua Zhang, Jian-Zhong Li, Tianbin Song, Xue-Min Liu, Hui Wang, Ce Zhang, Guo-Lin Ma, Hui Zhang, Kefeng Li

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Ai-Ling CuiAnatomy Department, Changzhi Medical College, Changzhi, Shanxi.
Ying-Hua ZhangKey Laboratory of Tissue Regeneration of Henan Province, Xinxiang Medical University, Xinxiang, Henan.
Jian-Zhong LiClinical Laboratory of Heji Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi.
Tianbin SongDepartment of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing.
Xue-Min LiuAnatomy Department, Changzhi Medical College, Changzhi, Shanxi.
Hui WangKey Laboratory of Tissue Regeneration of Henan Province, Xinxiang Medical University, Xinxiang, Henan.
Ce ZhangDepartment of Physiology, Shanxi Medical University, Taiyuan, Shanxi.
Guo-Lin MaDepartment of Radiology, China-Japan Friendship Hospital, Beijing.
Hui ZhangDepartment of Radiology, First Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Kefeng LiSchool of Medicine, University of California - San Diego, San Diego, CA, USA.
Changzhi Medical College · CNShanxi Medical University · CNXinxiang Medical University · CNCapital Medical University · CNChina-Japan Friendship Hospital · CNUniversity of San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnimals, NewbornCells, CulturedCerebral CortexDose-Response Relationship, DrugIntracellular Signaling Peptides and ProteinsMitochondriaNeuronsNitric OxideN-MethylaspartateRatsRats, WistarReactive Oxygen SpeciesReceptors, N-Methyl-D-AspartateStructure-Activity RelationshiphumaninIntracellular Signaling Peptides and ProteinsNitric OxideN-MethylaspartateReactive Oxygen SpeciesReceptors, N-Methyl-D-Aspartatealleviationhumaninmitochondrial dysfunctionNMDA-induced toxicity

Identifiers

PMID28458518
PMCPMC5402890
OpenAlexW2606717783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.