Evidence map›Paper›PMID 28458444›Full record

ArticleDisease markers2017

Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.

Katherine E Beaney, Andrew J P Smith, Lasse Folkersen, Jutta Palmen, S Goya Wannamethee, Barbara J Jefferis, Peter Whincup, Tom R Gaunt, Juan P Casas, Yoav Ben-Shlomo and 11 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 3 countries.

Katherine E BeaneyCentre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, University Street, London, UK.ORCID 0000-0001-7544-2055
Andrew J P SmithCentre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, University Street, London, UK.
Lasse FolkersenCardiovascular Medicine Unit, Center for Molecular Medicine and Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden.
Jutta PalmenCentre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, University Street, London, UK.
S Goya WannametheeDepartment of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London, UK.
Barbara J JefferisDepartment of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London, UK.
Peter WhincupPopulation Health Research Institute, St George's University of London, Cranmer Terrace, London, UK.
Tom R GauntMRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
Juan P CasasFarr Institute of Health Informatics Research, University College London, London, UK.
Yoav Ben-ShlomoSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Jacqueline F PriceCentre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.
Meena KumariDepartment of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, UK.
Andrew WongMRC Unit for Lifelong Health and Ageing, London, UK.
Ken OngMRC Unit for Lifelong Health and Ageing, London, UK.ORCID 0000-0003-4689-7530
Rebecca HardyMRC Unit for Lifelong Health and Ageing, London, UK.
Diana KuhMRC Unit for Lifelong Health and Ageing, London, UK.
Nicholas WarehamMRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
Mika KivimakiDepartment of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, UK.
Per ErikssonCardiovascular Medicine Unit, Center for Molecular Medicine and Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden.
Steve E HumphriesCentre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, University Street, London, UK.ORCID 0000-0002-8221-6547
Ucleb ConsortiumInstitute of Cardiovascular Science, University College London, London, UK.
British Heart Foundation · GBMRC Unit for Lifelong Health and Ageing · GBUniversity College London · GBKarolinska University Hospital · SEUniversity of Bristol · GBAddenbrooke's Hospital · GBFarr Institute · GBSt George's, University of London · GBUniversity of Edinburgh · GBUniversity of Essex · GB

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
British Heart Foundation FS/13/6/29977British Heart Foundation PG/09/024/26857British Heart Foundation PG/13/66/30442British Heart Foundation RG/07/008/23674British Heart Foundation RG/08/008/25291British Heart Foundation RG/08/013/25942British Heart Foundation RG/10/12/28456British Heart Foundation RG/13/16/30528Medical Research Council G0500877Medical Research Council MC_UU_12013/8Medical Research Council MC_UU_12015/2Medical Research Council MC_UU_12019/1Medical Research Council MR/K013351/1NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic LociChromosomes, Human, Pair 21Coronary DiseaseHep G2 CellsHumansLong QT SyndromePolymorphism, Single Nucleotide

Identifiers

PMID28458444
PMCPMC5387827
OpenAlexW2601822410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.