Evidence map›Paper›PMID 28458319›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Overlap of IgG4-related Disease and Multicentric Castleman's Disease in a Patient with Skin Lesions.

Hiroki Mochizuki, Manako Kato, Takakazu Higuchi, Ryosuke Koyamada, Satoru Arai, Sadamu Okada, Hikaru Eto

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Pulmonary plasma cell disorders: histopathology, diagnosis, and clinical perspectives.Virchows Archiv : an international journal of pathology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hiroki MochizukiInternal Medicine, St. Luke's International Hospital, Japan.
Manako KatoInternal Medicine, St. Luke's International Hospital, Japan.
Takakazu HiguchiDivision of Hematology, St. Luke's International Hospital, Japan.
Ryosuke KoyamadaDivision of Hematology, St. Luke's International Hospital, Japan.
Satoru AraiDepartment of Dermatology, St. Luke's International Hospital, Japan.
Sadamu OkadaDivision of Hematology, St. Luke's International Hospital, Japan.
Hikaru EtoDepartment of Dermatology, St. Luke's International Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59-year-old man presented with multiple dark red erythemas with induration, anemia, and polyclonal hypergammaglobulinemia. A skin biopsy revealed the infiltration of lymphocytes and plasma cells and he was initially diagnosed with multicentric Castleman's disease (MCD). Glucocorticoid treatment was only partially effective. Four years later, the patient's bilateral lacrimal glands gradually became enlarged and a biopsy revealed dense lymphocyte and plasma cell infiltration with an IgG4+/IgG+ plasma cell ratio of 70%. The patient was diagnosed with IgG4-related disease (RD). Rituximab only had a slight effect. This case demonstrates that overlapping features of IgG4-RD and MCD may present in a single patient, which suggests a shared pathogenesis.

Indexed as

Castleman DiseaseGlucocorticoidsHumansHypergammaglobulinemiaImmunoglobulin GImmunologic FactorsMaleMiddle AgedPlasma CellsRituximabSkin DiseasesTreatment OutcomeGlucocorticoidsImmunoglobulin GImmunologic FactorsRituximabIgG4-related diseasemulticentric Castleman's diseaserituximabskin lesion

Identifiers

PMID28458319
PMCPMC5478574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.