ArticleInternal medicine (Tokyo, Japan)2017
Clinical Features of Patients with Basedow's Disease and High Serum IgG4 Levels.
Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Study on the correlation between serum IgG4/IgG levels and the development of Graves' ophthalmopathy.Scientific reports · 2025Article
- IgG4 serum levels in Graves' orbitopathy.Journal of endocrinological investigation · 2024Article
- High IgG4 serum concentration is associated with active Graves orbitopathy.Frontiers in endocrinology · 2023Observational
- Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review.Endocrinology and metabolism (Seoul, Korea) · 2022Review
- The characteristics and clinical significance of elevated serum IgG4/IgG levels in patients with Graves' disease.Endocrine · 2022Observational
- IgG4 as a Biomarker in Graves' Orbitopathy.Mediators of inflammation · 2021Review
- Potential Importance of a Histopathological Analysis in Thyroidal Diseases with High Serum IgG4 Levels.Internal medicine (Tokyo, Japan) · 2018Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Objective IgG4-related disease is a recently characterized condition presenting with high blood IgG4 levels, swelling of organs, and hypertrophic lesions. This disease is associated with thyroid disease, Hashimoto's disease, and Riedel's thyroiditis. However, there is little information on the association between IgG4-related disease and Basedow's disease. We herein defined the clinical features of patients with Basedow's disease and high IgG4 levels. Methods We compared two groups of patients with Basedow's disease (n=72) who had either normal IgG4 levels (<135 mg/dL; n=67) or high IgG4 levels (≥135 mg/dL; n=5 [6.9%], mean IgG4: 206±116 mg/dL, IgG4/IgG ratio: 10.6%±3.3%). Patients Seventy-two newly diagnosed, untreated patients with Basedow's disease. Results Compared to the normal IgG4 group, patients in the high IgG4 group were predominantly male and showed a significantly higher thyroid low-echo score (1.8±0.4 vs. 1.2±0.5) and eosinophil count (363±354/mm
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