ArticleThe Journal of reproduction and development2017
Ultrastructural characteristics of human oocytes vitrified before and after in vitro maturation.
Article in The Journal of reproduction and development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Impact of Maturation and Vitrification Time of Human GV Oocytes on the Metaphase Plate Configuration.International journal of molecular sciences · 2021Trial
- Media temperature control: a potentially important quality control parameter in human oocyte vitrification.Reproduction & fertility · 2026Observational
- Stereological study of organelle distribution in human mature oocytes.Scientific reports · 2024Article
- Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM.Journal of ovarian research · 2023Article
- Potential Development of Vitrified Immature Human Oocytes: Influence of the Culture Medium and the Timing of Vitrification.International journal of molecular sciences · 2022Article
- An interpretable and versatile machine learning approach for oocyte phenotyping.Journal of cell science · 2022Article
- Exploring the Developmental Potential of Human Germinal Vesicle Oocytes Aiming at Fertility Preservation: Can We Increase the Yields of Competent Oocytes through IVM Combined with Vitrification?Journal of clinical medicine · 2022Article
- Matrix-free 3D culture supports human follicular development from the unilaminar to the antral stage in vitro yielding morphologically normal metaphase II oocytes.Human reproduction (Oxford, England) · 2021Article
- Cytoplasmic maturation in human oocytes: an ultrastructural study †.Biology of reproduction · 2021Article
- Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress.Oxidative medicine and cellular longevity · 2021Review
- Looking back and looking forward: contributions of electron microscopy to the structural cell biology of gametes and fertilization.Open biology · 2020Review
- OocyteTurkish journal of obstetrics and gynecology · 2018Review
- Vitrification of human immature oocytes before and after in vitro maturation: a review.Journal of assisted reproduction and genetics · 2017Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of an effective program that combines in vitro maturation (IVM) and cryopreservation for immature oocytes would represent a novel advance for in vitro fertilization (IVF), especially as a means to preserve the fertility of women in unique situations. The aim of this study was to analyze the ultrastructural characteristics of human oocytes, obtained after controlled ovarian stimulation, to determine whether IVM is best performed before or after vitrification. To this end, we analyzed the following features in a total of 22 MII oocytes: size, zona pellucida and perivitelline space, mitochondria number, M-SER (mitochondria-smooth endoplasmic reticulum) aggregates and M-V (mitochondria-vesicle) complexes, the number of cortical granules and microvilli, and the presence of vacuolization using transmission electron microscopy (TEM). Each oocyte presented a rounded shape, with an intact oolemma, and was surrounded by a continuous zona pellucida and perivitelline space. Statistical analysis comparing oocytes vitrified before or after IVM indicated that there were no significant differences between examined characteristics.
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