Evidence map›Paper›PMID 28457476›Full record

ArticleJournal of the American Dental Association (1939)2017

Mechanisms underlying methamphetamine-related dental disease.

Jason Clague, Thomas R Belin, Vivek Shetty

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Dental Association (1939), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Mucocutaneous Manifestations of Recreational Drug Use.American journal of clinical dermatology · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Oral Microbiota Profile of Individuals Who Abuse Methamphetamine.Frontiers in cellular and infection microbiology · 2021
    Article
  13. Cocaine and methamphetamine: Pharmacology and dental implications.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2020
    Review
  14. Oral manifestations in drug users: A review.Journal of clinical and experimental dentistry · 2020
    Review
  15. Periodontal status of current methamphetamine users.Journal of the American Dental Association (1939) · 2018
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jason Clague
Thomas R Belin
Vivek Shetty
University of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
The Oral & Dental Consequences of Methamphetamine UseR01DA025680 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHETTY, VIVEK · 2010 to 2013
$1.9M
NCATS NIH HHS UL1 TR000124NIDA NIH HHS R01 DA025680
6 · The paper itself

Abstract

backgroundThe authors clarified the causal mechanisms underlying the high prevalence of dental disease encountered in people who habitually use methamphetamine (meth).

methodsUsing a stratified sampling approach, the authors conducted comprehensive oral examinations and psychosocial assessments for 571 study participants who used meth. Three calibrated dentists, who used National Health and Nutrition Examination Survey (NHANES) protocols, characterized the study participants' dental disease. The authors also collected data related to study participants' history of meth use and other attributes linked to dental disease.

resultsStudy participants who used meth manifested higher rates of xerostomia and caries experience compared with NHANES control participants. Participants who used meth had a higher level of daily consumption of sugary beverages compared with NHANES control participants. Smoking meth did not increase caries experience over other modes of intake. Dental hygiene was a significant determinant of dental health outcomes.

conclusionsMode of intake and frequency of meth use have a minimal impact on dental health outcomes. Behaviors, such as sugary beverage consumption and poor oral hygiene, better explain dental health outcomes. PRACTICAL IMPLICATIONS: Having a better understanding of the causal mechanisms of "meth mouth" sets the stage for clinicians to provide more personalized interventions and management of dental disease in people who use meth.

Indexed as

AdultAmphetamine-Related DisordersCarbonated BeveragesDental CariesEducational StatusFemaleHumansMaleMethamphetamineMiddle AgedNutrition SurveysRacial GroupsStomatognathic DiseasesXerostomiaMethamphetaminecariesMethamphetamineoral healthstatisticsxerostomia

Identifiers

PMID28457476
PMCPMC6100769
OpenAlexW2608195881

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.