Evidence map›Paper›PMID 28456805›Full record

ReviewInternational archives of allergy and immunology2017

Allergens of Blomia tropicalis: An Overview of Recombinant Molecules.

Eduardo Santos da Silva, Claudia Asam, Peter Lackner, Heidi Hofer, Michael Wallner, Carina Silva Pinheiro, Neuza Maria Alcântara-Neves, Fatima Ferreira

Abstract readReview
In one paragraph

Review in International archives of allergy and immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Engineering Chimeric Hypoallergens for Safer and More Effective House Dust Mite Allergy Vaccines.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  3. Article
  4. Article
  5. Indoor Allergen Interventions in Homes and Schools for Managing Asthma.The journal of allergy and clinical immunology. In practice · 2025
    Review
  6. Review
  7. Correlation ofAsia Pacific allergy · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. The Allergenic Activity of Blo t 2, aInternational journal of molecular sciences · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Conjunctival Provocation Test WithFrontiers in allergy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eduardo Santos da SilvaLaboratório de Alergia e Acarologia, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Claudia Asam
Peter Lackner
Heidi Hofer
Michael Wallner
Carina Silva Pinheiro
Neuza Maria Alcântara-Neves
Fatima Ferreira

Funding

Austrian Science Fund FWF P 27589
6 · The paper itself

Abstract

Allergic diseases are considered a major problem for healthcare systems in both developed and developing countries. House dust mites are well-known triggers of allergic manifestations. While the Dermatophagoides genus is widely distributed globally, Blomia tropicalis is the most prominent mite species in the tropical and subtropical regions of the world. Over the last decades, an increase in sensitization rates to B. tropicalis has been reported, leading to increased research efforts on Blomia allergens. In fact, 8 new allergens have been identified and characterized to different degrees. Here, we provide an overview of recent developments concerning the identification and production of recombinant Blomia allergens, as well as their structural and immunological characterization. Although considerable progress has been achieved, detailed molecule-based studies are still needed to better define the clinical relevance of Blomia allergens. Thus, the establishment of a well-standardized and fully characterized panel of allergens remains a challenge for the development of better diagnosis and therapy of allergic diseases induced by B. tropicalis.

Indexed as

AllergensArthropod ProteinsAnimalsDesensitization, ImmunologicHumansHypersensitivityMitesProtein Processing, Post-TranslationalRecombinant ProteinsAllergensArthropod ProteinsRecombinant ProteinsBlomia tropicalisCross-reactivityImmunoglobulin E epitopesRecombinant allergensSecondary structureT-cell epitopesThree-dimensional structure

Identifiers

PMID28456805
PMCPMC5472214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.