ReviewThe Lancet. Oncology2017
The future of personalised radiotherapy for head and neck cancer.
Review in The Lancet. Oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03431363 (A Pilot Study to Assess the Role of Cannabis Added to the Supportive Care Regimen During Chemoradiation for Head and Neck Cancer), which is not on this map. Cited by 104 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study to Assess the Role of Cannabis Added to the Supportive Care Regimen During Chemoradiation for Head and Neck Cancer
Who cites it
104 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Deep learning algorithm performance in contouring head and neck organs at risk: a systematic review and single-arm meta-analysis.Biomedical engineering online · 2023Pooled it
- Is COLasers in medical science · 2023Pooled it
- Predictive value of health-related quality of life on radiotherapy-related toxicities in patients with head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Optimizing immunotherapy for head and neck squamous cell carcinoma: recent advances and future directions.Annals of medicine · 2026Review
- Article
- Variable-interval temporal feathering to optimize organs-at-risk repair for head and neck adaptive radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Long-term functional and nutritional outcomes in patients with retropharyngeal lymph node-positive hypopharyngeal cancer treated with concurrent chemoradiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Uncover This Tech Term: Tumor Habitat Analysis.Korean journal of radiology · 2026Article
- 75 Years of Mathematical Oncology.bioRxiv : the preprint server for biology · 2026Article
- Comparison of surgical and non surgical treatment strategies for non metastatic oropharyngeal cancer using inverse probability weighting.Discover oncology · 2025Article
- Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making.Cancer research · 2025Review
- Beyond Standard Radiotherapy: an AI-Driven Framework for Personalized Radiotherapy with a Four-Step Classification in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients.Current oncology reports · 2025Review
- Radiation therapy response prediction for head and neck cancer using multimodal imaging and multiview dynamic graph autoencoder feature selection.Medical physics · 2025Article
- Implementing a patient engagement framework to enhance nutritional status in outpatients receiving radiotherapy for head and neck cancer.Nutrition research and practice · 2025Article
- Dosimetric Comparison of Noncoplanar VMAT Without Rotating the Patient Couch Versus Conventional Coplanar/Noncoplanar VMAT for Head and Neck Cancer: First Report of Dynamic Swing Arc.Advances in radiation oncology · 2025Article
- Transient radiation-induced severe obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Targeting ferroptosis for improved radiotherapy outcomes in HPV-negative head and neck squamous cell carcinoma.Molecular oncology · 2025Article
- Article
- Identification of a novel immune-related gene signature by single-cell and bulk sequencing for the prediction of the immune landscape and prognosis of breast cancer.Cancer cell international · 2024Article
- Radioprotection Performance Evaluation of 3D-Printed and Conventional Heat-Cured Dental Resins for Radiotherapy Prostheses.Journal of functional biomaterials · 2024Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Radiotherapy has long been the mainstay of treatment for patients with head and neck cancer and has traditionally involved a stage-dependent strategy whereby all patients with the same TNM stage receive the same therapy. We believe there is a substantial opportunity to improve radiotherapy delivery beyond just technological and anatomical precision. In this Series paper, we explore several new ideas that could improve understanding of the phenotypic and genotypic differences that exist between patients and their tumours. We discuss how exploiting these differences and taking advantage of precision medicine tools-such as genomics, radiomics, and mathematical modelling-could open new doors to personalised radiotherapy adaptation and treatment. We propose a new treatment shift that moves away from an era of empirical dosing and fractionation to an era focused on the development of evidence to guide personalisation and biological adaptation of radiotherapy. We believe these approaches offer the potential to improve outcomes and reduce toxicity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.